| Company Name: |
Sigma-Aldrich |
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021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
ZONIPORIDE manufacturers
- Zoniporide
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- $45.00
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2026-04-22
- CAS:241800-98-6
- Purity: 99.74%
- Supply Ability: 10g
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| | ZONIPORIDE Basic information |
| Product Name: | ZONIPORIDE | | Synonyms: | N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine;CP 597396;ZONIPORIDE;N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate;Zoniporide hydrochloride hydrate;1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-;N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide;[1-(quinolin-5-yl)-5-cycloPropyl-1H-pyrazole-4-formyl]guanidine | | CAS: | 241800-98-6 | | MF: | C17H16N6O | | MW: | 320.35 | | EINECS: | | | Product Categories: | | | Mol File: | 241800-98-6.mol |  |
| | ZONIPORIDE Chemical Properties |
| density | 1.54 | | storage temp. | 2-8°C | | solubility | H2O: soluble2mg/mL, clear (warmed) | | form | powder | | pka | 11.44±0.46(Predicted) | | color | white to tan | | Water Solubility | H2O: 2mg/mL, clear (warmed) | | InChI | 1S/C17H16N6O.ClH.H2O/c18-17(19)22-16(24)12-9-21-23(15(12)10-6-7-10)14-5-1-4-13-11(14)3-2-8-20-13;;/h1-5,8-10H,6-7H2,(H4,18,19,22,24);1H;1H2 | | InChIKey | UCIJUEGJEFJRMP-UHFFFAOYSA-N | | SMILES | O.Cl.NC(=N)NC(=O)c1cnn(-c2cccc3ncccc23)c1C4CC4 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | ZONIPORIDE Usage And Synthesis |
| Uses | Zoniporide hydrochloride hydrate has been used for the inhibition of sodium-hydrogen exchanger isoform 1 (NHE-1) in rat models. It has also been used in cytotoxicity assay and to study its effect on lymphocytic choriomeningitis virus multiplication. | | Biochem/physiol Actions | Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM. |
| | ZONIPORIDE Preparation Products And Raw materials |
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