| Product Identification | Back to Contents | 【Product Name】
Acemetacin | 【Synonyms】
1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid carboxymethyl ester
1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid carboxymethyl ester
2-[2-[1-[(4-Chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl]acetyloxy]acetic acid | 【CAS】
53164-05-9 | 【Formula】
C21H18ClNO6 | 【Molecular Weight】
415.83 | 【EINECS】
258-403-4 | 【RTECS】
NL3521400 | 【RTECS Class】
Drug; Reproductive Effector | 【Merck】
12,27 | 【Beilstein/Gmelin】
501672 | 【Beilstein Reference】
5-22-05-00241 |
| Physical and Chemical Properties | Back to Contents | 【Solubility in water】
Slightly soluble | 【Boiling Point】
637 | 【Vapor Pressure】
4E-17 (25 C) | 【pKa/pKb】
2.60 (pKa) | 【Heat Of Vaporization】
98.9 kJ/mol | 【Usage】
An nsaid that specifically potentiates the cytoxicity of anthracyclines. |
| First Aid Measures | Back to Contents | 【Ingestion】
If swallowed, wash out mouth with water provided person is conscious. Call a physician. | 【Inhalation】
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. | 【Skin】
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician. | 【Eyes】
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician. |
| Hazards Identification | Back to Contents | 【Inhalation】
TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed. | 【Skin】
Contact with molten substance may cause severe burns to skin and eyes. See Inhalation. | 【Eyes】
See Inhalation. | 【Ingestion】
See Inhalation. | 【Hazards】
Emits toxic fumes under fire conditions. | 【EC Risk Phrase】
26/27/28 | 【EC Safety Phrase】
22 25 36/37/39 45 | 【UN (DOT)】
2811 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing. | 【Respirators】
Wear positive pressure self-contained breathing apparatus (SCBA). | 【Exposure Effects】
Very toxic by inhalation, in contact with skin and if swallowed. |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
339 | 【Fire Fighting】
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. | 【Fire Potential】
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. |
| Stability and Reactivity | Back to Contents | 【Stability】
Stable at normal temperatures and pressures. | 【Decomposition】
Carbon monoxide, Carbon dioxide, Nitrogen oxides. | 【Combustion Products】
Fire may produce irritating, corrosive and/or toxic gases. |
|
| Company Name: |
CSPC Ouyi Pharmaceutical Co., Ltd. |
| Tel: |
+86-311-87896753,13357827713,15614137668 |
| Fax: |
+86-311-87893974 |
| WebSite: |
www.chemicalbook.com/ShowSupplierProductsList19714/0.htm |
| Company Name: |
J & K SCIENTIFIC LTD. |
| Tel: |
010-82848833 400-666-7788 |
| Fax: |
86-10-82849933 |
| WebSite: |
http://www.jkchemical.com |
| Company Name: |
Adamas Reagent, Ltd. |
| Tel: |
400-6009262 16621234537 |
| Fax: |
021-64823266 |
| WebSite: |
www.tansoole.com |
|