| Product Identification | Back to Contents | 【Product Name】
CoA | 【Synonyms】
[5-(6-Aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-(2-sulfanylethylcarbamoyl)ethylcarbamoyl]propoxy]phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid
Adenosine 5'-(trihydrogen diphosphate) 3'-(dihydrogen phosphate) P'-[(R)-3-hydroxy-4-[[3-[(2-mercaptoethyl)amino]-3-oxopropyl]amino]-2,2-dimethyl-4-oxobutyl] ester
Aluzime
CoA-SH
Coenzyme ASH
D-Coenzyme A
Thiophene, 2-methoxy- | 【CAS】
16839-97-7 | 【CAS】
85-61-0 | 【Formula】
C21H36N7O16P3S | 【Formula】
C5H6OS | 【Molecular Weight】
767.53 | 【Molecular Weight】
114.16 | 【EINECS】
201-619-0 | 【EINECS】
240-863-2 | 【Merck】
12,2531 | 【Beilstein/Gmelin】
106271 | 【Beilstein/Gmelin】
77809 | 【Beilstein Reference】
4-26-00-03663 | 【Beilstein Reference】
5-17-03-00288 |
| Physical and Chemical Properties | Back to Contents | 【Appearance】
Clear golden liquid. With a stench. | 【Appearance】
Yellow solid. | 【Melting Point】
-5 | 【Boiling Point】
146 - 147 | 【Density】
1.1335 g/cm3 (20 C) | 【pKa/pKb】
1.14 (pKa) | 【Usage】
Plays a significant role in many important biochemical pathways including the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. | 【Vapor Density】
3.9 | 【Refractive Index】
1.53 (20 C) |
| First Aid Measures | Back to Contents | 【Ingestion】
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. | 【Ingestion】
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. | 【Inhalation】
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. | 【Inhalation】
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Vapors may cause dizziness or suffocation. | 【Skin】
May cause skin irritation. The toxicological properties of this material have not been fully investigated. | 【Skin】
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. | 【Eyes】
May cause eye irritation. The toxicological properties of this material have not been fully investigated. | 【Eyes】
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
| Handling and Storage | Back to Contents | 【Storage】
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. | 【Storage】
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Deep freeze (below -20 C). | 【Handling】
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. | 【Handling】
Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. |
| Hazards Identification | Back to Contents | 【Ingestion】
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. | 【Ingestion】
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. | 【Inhalation】
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. | 【Skin】
May cause skin irritation. | 【Eyes】
May cause eye irritation. | 【EC Risk Phrase】
R 10 | 【EC Safety Phrase】
S 23 24/25 | 【UN (DOT)】
1993 |
| Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Personal Protection】
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. | 【Respirators】
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary. | 【Respirators】
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. |
| Fire Fighting Measures | Back to Contents | 【Flash Point】
43 | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam. | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
| Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. | 【Small spills/leaks】
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. |
| Stability and Reactivity | Back to Contents | 【Incompatibilities】
Oxidizing agents. | 【Stability】
Stable at room temperature in closed containers under normal storage and handling conditions. | 【Stability】
Stable under normal temperatures and pressures. | 【Incompatibilities】
Strong oxidizing agents. | 【Decomposition】
Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide. | 【Decomposition】
Nitrogen oxides, carbon monoxide, oxides of sulfur, oxides of phosphorus, irritating and toxic fumes and gases, carbon dioxide, hydrogen sulfide. |
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