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Coenzyme A

Coenzyme A
Coenzyme A structure
CAS No.
85-61-0
Chemical Name:
Coenzyme A
Synonyms
COA;Coalip;Lucina;COA-SH;Aluzime;Thiol-CoA;SHUIRUJIE;COENZYME A;CONENZYME A;Coenzyme ASH
CBNumber:
CB8854470
Molecular Formula:
C21H36N7O16P3S
Formula Weight:
767.53
MOL File:
85-61-0.mol

Coenzyme A Properties

Density 
1.96±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
9.6 (thiol); pK 6.4 (secondary phosphate); pK 4.0 (adenine NH3+)
Merck 
13,2491
BRN 
77809
EWG's Food Scores
1
FDA UNII
SAA04E81UX
EPA Substance Registry System
Coenzyme A (85-61-0)
SAFETY
  • Risk and Safety Statements
Safety Statements  24/25
WGK Germany  3
1-10
TSCA  Yes
NFPA 704
0
1 0

Coenzyme A price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C4282 Coenzyme A hydrate ≥85% (UV, HPLC) 85-61-0 10mg $65.5 2021-12-16 Buy
Sigma-Aldrich C4282 Coenzyme A hydrate ≥85% (UV, HPLC) 85-61-0 25mg $109 2021-12-16 Buy
Alfa Aesar J13787 Coenzyme A trihydrate, free acid, Affymetrix/USB 85-61-0 50mg $108.19 2021-12-16 Buy
Alfa Aesar J13787 Coenzyme A trihydrate, free acid, Affymetrix/USB 85-61-0 1g $1350.25 2021-12-16 Buy
Cayman Chemical 16147 Coenzyme A ≥98% 85-61-0 25mg $91 2021-12-16 Buy

Coenzyme A Chemical Properties,Uses,Production

Description

Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. About 4% of cellular enzymes utilize CoA as a substrate. It is synthesized from pantothenic acid in a 5-step process that requires ATP. The pantothenate kinase step of the CoA biosynthetic pathway has been identified as a target for the development of antibacterial compounds.

Chemical Properties

yellowish lyophilisate

Uses

A hydrated form of Coenzyme A (CoA) is a useful biochemical research chemical, used in the preparation of high-yielding cell-free protein synthesis platforms.

Definition

ChEBI: Tetraanion of coenzyme A.

General Description

Coenzyme A is structurally composed of 2-aminoethanethiol, pantothenic acid and phosphorylated adenosine phosphate.

Biochem/physiol Actions

Coenzyme A is a cofactor involved in acyl group transfer. It is essential for carbohydrate, lipid and protein metabolism. Coenzyme A acts as a cofactor for vitamin B coenzymes.

Purification Methods

The white powder is best stored in an inert atmosphere in the dark in sealed ampoules after drying in vacuo over P2O5 at 34o. It has UV: max 259 nm ( 16,800) in H2O. [Buyske et al. J Am Chem Soc 76 3575 1954.] It is soluble in H2O but insoluble in EtOH, Et2O and M2CO. It is readily oxidised in air and is best kept as the more stable trilithium salt [Moffat & Khorana J Am Chem Soc 83 663 1961; see also Beinert et al. J Biol Chem 200 384 1953, De Vries et al. J Am Chem Soc 72 4838 1950, Gregory et al. J Am Chem Soc 74 854 1952 and Baddiley Adv Enzymol 16 1 1955]. [Beilstein 26 III/IV 3663.]

Coenzyme A Preparation Products And Raw materials

Raw materials

Preparation Products


Coenzyme A Suppliers

Global( 191)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070
product@chemlin.com.cn CHINA 3013 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 26782 60
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29954 58
HEBEI YINGONG NEW MATERIAL TECHNOLOGY CO.,LTD
+8619933070948
claire@hbyingong.com China 684 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 37282 58
TopScience Biochemical
00852-68527855
00852-26406298 info@itopbiochem.com China Hong Kong 904 58
HENAN BON INDUSTRIAL CO.,LTD
0371-55170695
info@hnbon.com CHINA 26742 58
CONIER CHEM AND PHARMA LIMITED
86-18523575427
sales@conier.com China 47498 58

View Lastest Price from Coenzyme A manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-12-01 Coenzyme A
85-61-0
US $1.90 / KG 1KG 99% 10 ton Hebei Crovell Biotech Co Ltd
2021-10-29 Coenzyme A
85-61-0
US $120.00 / ASSAYS 10g >99% 500kg/month HEBEI YINGONG NEW MATERIAL TECHNOLOGY CO.,LTD
2021-07-02 coenzyme A
85-61-0
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

Coenzyme A Spectrum


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