ChemicalBook >>Methimazole>>Methimazole(60-56-0)

Methimazole(60-56-0)

Methimazole(60-56-0)
Product IdentificationBack to Contents
【Product Name】

Methimazole
【Synonyms】

1-Methyl-3H-imidazole-2-thione
2-Mercapto-1-methylimidazole
Methimazole
【CAS】

60-56-0
【Formula】

C4H6N2S
【Molecular Weight】

114.17
【EINECS】

200-482-4
【RTECS】

NI8615000
【RTECS Class】

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
【Merck】

13,6000
【Beilstein/Gmelin】

108646
【Beilstein Reference】

5-24-01-00305
Physical and Chemical PropertiesBack to Contents
【Appearance】

Beige powder. Stench.
【Solubility in water】

Soluble
【Boiling Point】

155
【Vapor Pressure】

3 (25 C)
【Density】

1.36 g/cm3
【pKa/pKb】

11.64 (pKa)
【Partition Coefficient】

-.02
【Heat Of Vaporization】

39.2 kJ/mol
【Usage】

In cyanide-free silver electroplating. Therap cat: antihyperthyroid.
First Aid MeasuresBack to Contents
【Ingestion】

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Eyes】

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and StorageBack to Contents
【Storage】

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Hormones and antibiotics room.
【Handling】

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.
Hazards IdentificationBack to Contents
【Inhalation】

Causes irritation of the mucous membrane and upper respiratory tract. May cause sore throat, headache, and other effects similar to those of ingenstion.
【Skin】

May cause skin irritation. May cause an allergic reaction in certain individuals.
【Eyes】

May cause eye irritation.
【Ingestion】

In high doses may cause gastric irritation, nausea, vomiting, fever, skin rashes, and blood abnormalities including anemia. May be harmful if swallowed. May cause pain and stiffness in joints, paresthesias, headache, and loss or depigmentation of hair.
【EC Risk Phrase】

R 43 63
【EC Safety Phrase】

S 22 36/37
【UN (DOT)】

3335
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
【Exposure Effects】

Chronic exposure may cause reproductive disorders and teratogenic effects. Laboratory experiments have resulted in mutagenic effects. Chronic exposure can affect thyroid function. Chronic exposure may cause blood effects.
Fire Fighting MeasuresBack to Contents
【Flash Point】

47
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and ReactivityBack to Contents
【Stability】

Stable under normal temperatures and pressures. Light sensitive.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Transport InformationBack to Contents
【UN Number】

3335
【HS Code】

2933 29 90
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