ChemicalBook >> journal list>> iScience
iScience

iScience

IF:4.6 CiteScore:7.2 Articles:1972
Science has many big remaining questions. To address them, we will need to work collaboratively and across disciplines. The goal of iScience is to help fuel that type of interdisciplinary thinking. iScience is a new open-access journal from Cell Press that provides a platform for original research in the life, physical, and earth sciences. The primary criterion for publication in iScience is a significant contribution to a relevant field combined with robust results and underlying methodology. The advances appearing in iScience include both fundamental and applied investigations across this interdisciplinary range of topic areas. To support transparency in scientific investigation, we are happy to consider replication studies and papers that describe negative results. We know you want your work to be published quickly and to be widely visible within your community and beyond. With the strong international reputation of Cell Press behind it, publication in iScience will help your work garner the attention and recognition it merits. Like all Cell Press journals, iScience prioritizes rapid publication. Our editorial team pays special attention to high-quality author service and to efficient, clear-cut decisions based on the information available within the manuscript. iScience taps into the expertise across Cell Press journals and selected partners to inform our editorial decisions and help publish your science in a timely and seamless way.

Peripheral neuropathy associated with monomethyl auristatin E-based antibody-drug conjugates

Published: 20 October 2023 DOI: 10.1016/j.isci.2023.107778
Zhiwen Fu , Chen Gao , Tingting Wu , Lulu Wang , Shijun Li , Yu Zhang , Chen Shi

Targeting cuproptosis by zinc pyrithione in triple-negative breast cancer.

Published: 16 October 2023 DOI: 10.1016/j.isci.2023.108218
Xu Yang, Li Deng, Xianhong Diao, Siyuan Yang, Li Zou, Qin Yang, Jian Li, Jianyun Nie, Lina Zhao, Baowei Jiao

Deep learning enables stochastic optical reconstruction microscopy-like superresolution image reconstruction from conventional microscopy

Published: 4 October 2023 DOI: 10.1016/j.isci.2023.108145
Lei Xu , Shichao Kan , Xiying Yu , Ye Liu , Yuxia Fu , Yiqiang Peng , Yanhui Liang , Yigang Cen , Changjun Zhu , Wei Jiang

JUN mediates glucocorticoid resistance by stabilizing HIF1a in T?cell acute lymphoblastic leukemia

Published: 1 October 2023 DOI: 10.1016/j.isci.2023.108242
Zhijie Zhang, Jiangzhou Shi, Qifang Wu, Zijian Zhang, Xiaoyan Liu, Anqi Ren, Guanlin Zhao, Ge Dong, Han Wu, Jiaxuan Zhao, Yuan Zhao, Jia Hu, Hui Li, Tongcun Zhang, Fuling Zhou, Haichuan Zhu

Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of alveolar macrophages

Published: 21 July 2023 DOI: 10.1016/j.isci.2023.107197
Yue Wu, Shengen Shawn Hu, Ruixuan Zhang, Nick P Goplen, Xiaochen Gao, Harish Narasimhan, Ao Shi, Yin Chen, Ying Li, Chongzhi Zang, Haidong Dong, Thomas J Braciale, Bibo Zhu, Jie Sun

Tivantinib alleviates inflammatory diseases by directly targeting NLRP3.

Published: 17 March 2023 DOI: 10.1016/j.isci.2023.106062
Yi Huang , Yun Guo , Yan Zhou , Qian Huang , Yi Ru , Yingli Luo , Wen Xu

Microbiome assembly on Drosophila body surfaces benefits the flies to combat fungal infections

Published: 17 June 2022 DOI: 10.1016/j.isci.2022.104408
Song Hong , Yanlei Sun , Dapeng Sun , Chengshu Wang

A network-based computational and experimental framework for repurposing compounds toward the treatment of non-alcoholic fatty liver disease

Published: 18 March 2022 DOI: 10.1016/j.isci.2022.103890
Danae Stella Zareifi , Odysseas Chaliotis , Nafsika Chala , Nikos Meimetis , Maria Sofotasiou , Konstantinos Zeakis , Eirini Pantiora , Antonis Vezakis , George K. Matsopoulos , Georgios Fragulidis , Leonidas G. Alexopoulos

SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T?cell epitope mutations for impaired cellular immune response

Published: 18 March 2022 DOI: 10.1016/j.isci.2022.103934
Chanchan Xiao , Lipeng Mao , Zhigang Wang , Lijuan Gao , Guodong Zhu , Jun Su , Xiongfei Chen , Jun Yuan , Yutian Hu , Zhinan Yin , Jun Xie , Weiqing Ji , Haitao Niu , Feng Gao , Oscar Junhong Luo , Lianbo Xiao , Pengcheng Wang , Guobing Chen

Targeting Myeloid-derived Suppressor Cells to Attenuate Vasculogenic Mimicry and Synergistically Enhance the Anti-tumor Effect of PD-1 Inhibitor

Published: 17 December 2021 DOI:
Yinan Li , Kailiang Qiao , Xiaoyun Zhang , Haoyang Liu , Heng Zhang , Zhiyang Li , Yanrong Liu , Tao Sun

In situ observation of mitochondrial biogenesis as the early event of apoptosis

Published: 27 August 2021 DOI: 10.1016/j.isci.2021.103038
Chang-Sheng Shao, Xiu-Hong Zhou, Yu-Hui Miao, Peng Wang, Qian-Qian Zhang, Qing Huang