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Science Advances

IF:11.7 CiteScore:21.4 Articles:1937

Science Advances, an open-access journal by AAAS, publishes impactful research in diverse scientific areas. It aims for fair, fast, and expert peer review, providing freely accessible research to readers. Led by distinguished scientists, the journal supports AAAS's mission by extending Science magazine's capacity to identify and promote significant advances. Evolving digital publishing technologies play a crucial role in advancing AAAS's global mission for science communication and benefitting humankind.

Human cytomegalovirus UL36 inhibits IRF3-dependent immune signaling to counterbalance its immunoenhancement as apoptotic inhibitor.

Published: 4 October 2023 DOI: 10.1126/sciadv.adi6586
Yujie Ren, An Wang, Bowen Zhang, Wenting Ji, Xiao-Xu Zhu, Jing Lou, Muhan Huang, Yang Qiu, Xi Zhou

NPRC deletion attenuates cardiac fibrosis in diabetic mice by activating PKA/PKG and inhibiting TGF-β1/Smad pathways

Published: 2 August 2023 DOI:
Linlin Meng, Yue Lu, Xinlu Wang, Cheng Cheng, Fei Xue, Lin Xie, Yaoyuan Zhang, Wenhai Sui, Meng Zhang, Yun Zhang, Cheng Zhang

The p23 co-chaperone is a succinate-activated COX-2 transcription factor in lung adenocarcinoma tumorigenesis

Published: 30 June 2023 DOI: 10.1126/sciadv.ade0387
Zhenlong Yu, Yulin Peng, Jian Gao, Meirong Zhou, Lei Shi, Feng Zhao, Chao Wang, Xiangge Tian, Lei Feng, Xiaokui Huo, Baojing Zhang, Min Liu, Deyu Fang, Xiaochi Ma

Neuropilin 1 is an entry receptor for KSHV infection of mesenchymal stem cell through TGFBR1/2-mediated macropinocytosis.

Published: 24 May 2023 DOI: 10.1126/sciadv.adg1778
Zheng-Zhou Lu, Cong Sun, Xiaolin Zhang, Yingying Peng, Yan Wang, Yan Zeng, Nannan Zhu, Yan Yuan, Mu-Sheng Zeng

The super elongation complex drives transcriptional addiction in MYCN -amplified neuroblastoma

Published: 29 March 2023 DOI: 10.1126/sciadv.adf0005
Donghai Wang, Zhinang Yin, Honghong Wang, Liyuan Wang, Tianyu Li, Ruijing Xiao, Ting Xie, Ruyi Han, Rui Dong, Hudan Liu, Kaiwei Liang, Guoliang Qing

Structural basis for motilin and erythromycin recognition by motilin receptor

Published: 15 March 2023 DOI: 10.1126/sciadv.ade9020
Chongzhao You, Yumu Zhang, Youwei Xu, Peiyu Xu, Zhen Li, Huadong Li, Sijie Huang, Zecai Chen, Jingru Li, H. Eric Xu, Yi Jiang

Visible light–initiated radical 1,3-difunctionalization of β,γ-unsaturated ketones

Published: 9 December 2022 DOI: 10.1126/sciadv.abq8596
Ruihua Liu, Yang Tian, Jie Wang, Zemin Wang, Xiangqian Li, Chenyang Zhao, Ruoyu Yao, Shuo Li, Leifeng Yuan, Jinbo Yang, Dayong Shi

Astrocyte dysfunction drives abnormal resting-state functional connectivity in depression

Published: 16 November 2022 DOI: 10.1126/sciadv.abo2098
Jiaming Liu, Jia-Wen Mo, Xunda Wang, Ziqi An, Shuangyang Zhang, Can-Yuan Zhang, Peiwei Yi, Alex T. L. Leong, Jing Ren, Liang-Yu Chen, Ran Mo, Yuanyao Xie, Qianjin Feng, Wufan Chen, Tian-Ming Gao, Ed X. Wu, Yanqiu Feng, Xiong Cao

FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.

Published: 21 September 2022 DOI: 10.1126/sciadv.abq4831
Hua Jiang, Weixiang Bian, Yue Sui, Huanle Li, Han Zhao, Wenqi Wang, Xu Li

Human expandable pancreatic progenitor–derived β cells ameliorate diabetes

Published: 23 February 2022 DOI: 10.1126/sciadv.abk1826
Xiaojie Ma, Yunkun Lu, Ziyu Zhou, Qin Li, Xi Chen, Weiyun Wang, Yan Jin, Zhensheng Hu, Guo Chen, Qian Deng, Weina Shang, Hao Wang, Hongxing Fu, Xiangwei He, Xin-Hua Feng, Saiyong Zhu

Class I histone deacetylases (HDAC1-3) are histone lysine delactylases.

Published: 19 January 2022 DOI:
Carlos Moreno-Yruela, Di Zhang, Wei Wei, Michael Bæk, Wenchao Liu, Jinjun Gao, Daniela Danková, Alexander L. Nielsen, Julie E. Bolding, Lu Yang, Samuel T. Jameson, Jiemin Wong, Christian A. Olsen, Yingming Zhao

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