Chemical Safety Data Sheet MSDS / SDS

Dichlorophenylphosphine

Revision Date:2026-04-11Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: Dichlorophenylphosphine
CBnumber: CB7304468
CAS: 644-97-3
EINECS Number: 211-425-8
Synonyms: BPD,dichlorophenylphosphine

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P270 Do not eat, drink or smoke when using this product.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

Hazard statements

H335 May cause respiratory irritation

H314 Causes severe skin burns and eye damage

H301 Toxic if swalloed

SECTION 3: Composition/information on ingredients

Substance

Product name: Dichlorophenylphosphine
Synonyms: BPD,dichlorophenylphosphine
CAS: 644-97-3
EC number: 211-425-8
MF: C6H5Cl2P
MW: 178.98

SECTION 4: First aid measures

General Advice

Show this safety data sheet to the doctor in attendance. Immediate medical attention is required.

Eye Contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Skin Contact

Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.

Inhalation

If not breathing, give artificial respiration. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.
Remove to fresh air. Immediate medical attention is required.

Ingestion

Do NOT induce vomiting. Call a physician or poison control center immediately.

Most important symptoms and effects

Causes burns by all exposure routes. Product is a corrosive material. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation: Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting

Self-Protection of the First Aider

Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination.

Notes to Physician

Treat symptomatically. Symptoms may be delayed.

SECTION 5: Firefighting measures

Suitable Extinguishing Media

CO2, dry chemical, dry sand, alcohol-resistant foam.

Extinguishing media which must not be used for safety reasons

Contact with water liberates toxic gas. Water.

Specific Hazards Arising from the Chemical

Thermal decomposition can lead to release of irritating gases and vapors. The product causes burns of eyes, skin and mucous membranes. Reacts violently with water.

Protective Equipment and Precautions for Firefighters

As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors.

NFPA 704

HEALTH	3	Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE	1	Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
REACT	0	Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal Precautions

Ensure adequate ventilation. Use personal protective equipment as required. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak.

Environmental Precautions

Should not be released into the environment.

Methods for Containment and Clean Up

Soak up with inert absorbent material. Keep in suitable, closed containers for disposal. Do not expose spill to water.
Refer to protective measures listed in Sections 8 and 13.

SECTION 7: Handling and storage

Handling

Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Use only under a chemical fume hood. Do not breathe mist/vapors/spray. Do not ingest. If swallowed then seek immediate medical assistance. Do not allow contact with water. Handle under an inert atmosphere.

Storage

Keep away from water or moist air. Keep containers tightly closed in a dry, cool and well-ventilated place. Corrosives area. Store under an inert atmosphere. Air sensitive.

Specific Use(s)

Use in laboratories

SECTION 8: Exposure controls/personal protection

Control Parameters

Exposure Controls

Engineering Measures

Use only under a chemical fume hood. Ensure that eyewash stations and safety showers are close to the workstation location.
Wherever possible, engineering control measures such as the isolation or enclosure of the process, the introduction of process or equipment changes to minimise release or contact, and the use of properly designed ventilation systems, should be adopted to control hazardous materials at source.

Personal protective equipment

Eye Protection

Goggles (European standard - EN 166)

Hand Protection

Protective gloves

Glove material	Breakthrough time	Glove thickness	EU standard	Glove comments
Nitrile rubber	See manufacturers	-	EN 374	(minimum requirement)

Viton (R)

recommendations
Inspect gloves before use.
Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves.
(Refer to manufacturer/supplier for information)
Ensure gloves are suitable for the task: Chemical compatability, Dexterity, Operational conditions, User susceptibility, e.g.
sensitisation effects, also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion.
Remove gloves with care avoiding skin contamination.

Skin and body protection

Wear appropriate protective gloves and clothing to prevent skin exposure

Respiratory Protection

When workers are facing concentrations above the exposure limit they must use appropriate certified respirators.
To protect the wearer, respiratory protective equipment must be the correct fit and be used and maintained properly

Large scale/emergency use

Use a NIOSH/MSHA or European Standard EN 136 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced
Recommended Filter type: Organic gases and vapours filter Type A Brown conforming to
EN14387

Small scale/Laboratory use

Use a NIOSH/MSHA or European Standard EN 149:2001 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Recommended half mask:- Valve filtering: EN405; or; Half mask: EN140; plus filter, EN 141
When RPE is used a face piece Fit Test should be conducted

Hygiene Measures

Handle in accordance with good industrial hygiene and safety practice.

Environmental exposure controls

No information available.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

ColourClear colorless to slightly yellow
Molecular Weight178.99
Molecular FormulaC6 H5 Cl2 P
Oxidizing PropertiesNo information available
Explosive PropertiesNo information available
ViscosityNo data available
Decomposition TemperatureNo data available
Autoignition Temperature159 °C / 318.2 °F
Partition Coefficient (n-octanol/water)No data available
Solubility in other solventsNo information available
Water SolubilityReacts with water
Bulk DensityNot applicable Liquid
Specific Gravity / Density1.319
Vapor DensityNo data available (Air = 1.0)
Vapor PressureNo data available
Explosion LimitsNo data available
Flammability (solid,gas)Not applicable Liquid
Evaporation RateNo data available
Flash Point102 °C / 215.6 °F Method - Open cup
Boiling Point/Range225 °C / 437 °
F @ 760 mmHg
Softening PointNo data available
Melting Point/Range51 °C / -59.8 °F
pHNo information available
Odor ThresholdNo data available
Odorpungent
Physical StateLiquid
AppearanceClear

SECTION 10: Stability and reactivity

Stability

Reacts violently with water. Moisture sensitive. Air sensitive.

Hazardous Reactions

None under normal processing. Reacts violently with water.

Hazardous Polymerization

Hazardous polymerization does not occur.

Conditions to Avoid

Incompatible products. Excess heat. Exposure to moist air or water. Exposure to moisture.
Exposure to air.

Materials to avoid

Strong oxidizing agents.

Hazardous Decomposition Products

Carbon monoxide (CO). Carbon dioxide (CO2). Oxides of phosphorus. Phosphorus trihydride (phosphine). Hydrogen chloride gas.

SECTION 11: Toxicological information

Product Information

(a) acute toxicity;

Component	LD50 Oral	LD50 Dermal	LC50 Inhalation
Phenyl phosphorus dichloride	500-2000 mg/kg ( Rat )

(b) skin corrosion/irritation;

Category 1 B

(c) serious eye damage/irritation;

Category 1

(d) respiratory or skin sensitization;

Respiratory

No data available

Skin

No data available

(e) germ cell mutagenicity;

No data available

(f) carcinogenicity;

No data available
There are no known carcinogenic chemicals in this product

(g) reproductive toxicity;

No data available

(h) STOT-single exposure;

No data available

(i) STOT-repeated exposure;

No data available

Target Organs

None known.

(j) aspiration hazard;

No data available

Other Adverse Effects

The toxicological properties have not been fully investigated.

Symptoms / effects,both acute and Product is a corrosive material. Use of gastric lavage or emesis is contraindicated.

delayed

Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation: Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting

SECTION 12: Ecological information

Ecotoxicity effects

Do not empty into drains. Reacts with water so no ecotoxicity data for the substance is available.

Persistence and Degradability

Persistence

Soluble in water, Persistence is unlikely, based on information available.

Degradability

Reacts with water.

Degradation in sewage

Water reactive.

treatment plant

Bioaccumulative Potential

Bioaccumulation is unlikely; Product does not bioaccumulate due to reaction with water

Component	log Pow	Bioconcentration factor (BCF)
Phenyl phosphorus dichloride		2 - 10 dimensionless

Mobility in soil

The product is water soluble, and may spread in water systems Reacts with water Will likely be mobile in the environment due to its water solubility Is not likely mobile in the environment Highly mobile in soils

Endocrine Disruptor Information

This product does not contain any known or suspected endocrine disruptors

Persistent Organic Pollutant

This product does not contain any known or suspected substance

Ozone Depletion Potential

This product does not contain any known or suspected substance

SECTION 13: Disposal considerations

Waste from Residues/Unused Products

Waste is classified as hazardous. Dispose of in accordance with the European Directives on waste and hazardous waste. Dispose of in accordance with local regulations.

Contaminated Packaging

Dispose of this container to hazardous or special waste collection point.

Other Information

Waste codes should be assigned by the user based on the application for which the product was used. Do not empty into drains. Do not flush to sewer. Large amounts will affect pH and harm aquatic organisms.

SECTION 14: Transport information

Road and Rail Transport

UN-No

UN2798

Proper Shipping Name

PHENYLPHOSPHORUS DICHLORIDE

Hazard Class

Packing Group

IMDG/IMO

UN-No

UN2798

Proper Shipping Name

PHENYLPHOSPHORUS DICHLORIDE

Hazard Class

Packing Group

IATA

UN-No

UN2798

Proper Shipping Name

PHENYLPHOSPHORUS DICHLORIDE

Hazard Class

Packing Group

Special Precautions for User

No special precautions required

SECTION 15: Regulatory information

International Inventories

X = listed, China (IECSC), Europe (EINECS/ELINCS/NLP), U.S.A. (TSCA), Canada (DSL/NDSL), Philippines (PICCS), Japan (ENCS), Japan (ISHL), Australia (AICS), Korea (KECL).

Component	The Inventory of Hazardous Chemicals (2015 Edition)	List of dangerous goods GB 12268 - 2012	TCSI	IECSC	EINECS	TSCA	DSL	PICCS	ENCS	ISHL	AICS	KECL
Phenyl phosphorus dichloride	X	X	X	X	211-425-8	X	-	X	X	X	X	KE-05-0452

National Regulations

SECTION 16: Other information

Revision Summary

Not applicable.

Training Advice

Chemical hazard awareness training, incorporating labelling, Safety Data Sheets (SDS), Personal Protective Equipment (PPE) and hygiene.
Use of personal protective equipment, covering appropriate selection, compatibility, breakthrough thresholds, care, maintenance, fit and standards.
First aid for chemical exposure, including the use of eye wash and safety showers.
Fire prevention and fighting, identifying hazards and risks, static electricity, explosive atmospheres posed by vapours and dusts.
Chemical incident response training.

Legend

CAS

Chemical Abstracts Service

TSCA

United States Toxic Substances Control Act Section 8(b)
Inventory

EINECS/ELINCS

European Inventory of Existing Commercial Chemical
Substances/EU List of Notified Chemical Substances

DSL/NDSL

Canadian Domestic Substances List/Non-Domestic
Substances List

PICCS

Philippines Inventory of Chemicals and Chemical Substances

ENCS

Japanese Existing and New Chemical Substances

IECSC

Chinese Inventory of Existing Chemical Substances

AICS

Australian Inventory of Chemical Substances

KECL

Korean Existing and Evaluated Chemical Substances

NZIoC

New Zealand Inventory of Chemicals

WEL

Workplace Exposure Limit

TWA

Time Weighted Average

ACGIH

American Conference of Governmental Industrial Hygienists

IARC

International Agency for Research on Cancer

DNEL

Derived No Effect Level

PNEC

Predicted No Effect Concentration

RPE

Respiratory Protective Equipment

LD50

Lethal Dose 50%

LC50

Lethal Concentration 50%

EC50

Effective Concentration 50%

NOEC

No Observed Effect Concentration

POW

Partition coefficient Octanol:Water

PBT

Persistent, Bioaccumulative, Toxic

vPvB

very Persistent, very Bioaccumulative

ICAO/IATA

International Civil Aviation Organization/International Air
Transport Association

IMO/IMDG

International Maritime Organization/International Maritime
Dangerous Goods Code

ADR

European Agreement Concerning the International Carriage of
Dangerous Goods by Road

MARPOL

International Convention for the Prevention of Pollution from
Ships

OECD

Organisation for Economic Co-operation and Development

ATE

Acute Toxicity Estimate

BCF

Bioconcentration factor

VOC

(Volatile Organic Compound)

Key literature references and sources for data

https://echa.europa.eu/information-on-chemicals
Suppliers safety data sheet, Chemadvisor - LOLI, Merck index, RTECS

Disclaimer

The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.