Chemical Safety Data Sheet MSDS / SDS
Terbutylazine
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: Terbutylazine
- CBnumber: CB3315253
- CAS: 5915-41-3
- EINECS Number: 227-637-9
- Synonyms: TERBUTHYLAZINE;TERBUTHYLAZIN
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordWarning
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P314 Get medical advice/attention if you feel unwell.
Hazard statements
H302 Harmful if swallowed
H373 May cause damage to organs through prolonged or repeated exposure
H410 Very toxic to aquatic life with long lasting effects
Substance
- Product name: Terbutylazine
- Synonyms: TERBUTHYLAZINE;TERBUTHYLAZIN
- CAS: 5915-41-3
- EC number: 227-637-9
- MF: C9H16ClN5
- MW: 229.71
General advice
Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Consult a physician.
In case of eye contact
After eye contact: rinse out with plenty of water. Call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
Protection of first-aiders
For personal protection see section 8.
Notes to physician
No data available
Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
Specific hazards during fire fighting
Combustible. Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.
Hazardous combustion products
Carbon oxides Nitrogen oxides (NOx) Hydrogen chloride gas
Specific extinguishing methods
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Special protective equipment for fire-fighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
NFPA 704
1
0
0
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid inhalation of dusts. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
Handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture.
Avoidance of contact
Strong oxidizing agents
Storage
Further information on storage conditionsTightly closed. Dry.
Storage class
11, Combustible Solids
Recommended storage temperature
2 - 8 °C
Further information on storage stability
Moisture sensitive. Store under argon.
control parameter
Hazard composition and occupational exposure limitsDoes not contain substances with occupational exposure limits.
Engineering measures
No data available
Personal protective equipment
Respiratory protectionrequired when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Recommended Filter type
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Filter type P2
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Eye/face protection
The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer. These measures have to be properly documented.
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Safety glasses
Skin and body protection
Safety glasses
protective clothing
Hand protection
Material
Nitrile rubber
Break through time
480 min
Glove thickness
0.11 mm
Protective index
Full contact
Manufacturer
KCL 741 L
Material
Nitrile rubber
Break through time
480 min
Glove thickness
0.11 mm
Protective index
Splash contact
Manufacturer
KCL 741 L
Remarks
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D- 36124 Eichenzell, Internet: www.kcl.de).
Hygiene measures
Change contaminated clothing. Preventive skin protection recommended. Wash hands after working with substance.
Information on basic physicochemical properties
- SolubilityDMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 1 mg/ml
- Physical stateSolid
- Odor ThresholdNo data available
- pHNo data available
- Melting point/ range175.5 °C
Method: OECD Test Guideline 102 - Boiling point/boiling range> 224 °C
Decomposition: yes
Method: OECD Test Guideline 103 Decomposition - Flash point100 °C
Method: closed cup - Particle characteristics Particle sizeNo data available
- Molecular weight229.7 g/mol
- Surface tension71.8 mN/m, 20 °C, OECD Test Guideline 115
- Oxidizing propertiesnone
- Explosive propertiesNo data available
- Flow timeNo data available
- Viscosity, kinematicNo data available
- Viscosity, dynamicNo data available
- Decomposition temperatureNo data available
- Autoignition temperatureNo data available
- Partition coefficient: n-octanol/waterlog Pow: 3.4 (25 °C)
Method: Regulation (EC) No. 440/2008, Annex, A.8 Bioaccumulation is not expected. - Water solubility0.00664 g/l soluble (20 °C)
Method: OECD Test Guideline 105 - Density1.1880
- Relative density1.1880
- Relative vapor densityNo data available
- Vapor pressureNo data available
- Lower explosion limit / Lower flammability limitNo data available
- Upper explosion limit / Upper flammability limitNo data available
- Burning rateNo data available
Self-ignition : Method: Regulation (EC) No. 440/2008, Annex, A.16 does not ignite - Evaporation rateNo data available
- OdorNo data available
- Colorwhite
- Appearancecrystalline
Reactivity
Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical. The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.
Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
Possibility of hazardous reactions
No data available
Conditions to avoid
Strong heating.
Incompatible materials
Strong oxidizing agents
Hazardous decomposition
In the event of fire: see section 5 products
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - 1,000 - 1,590 mg/kg (US-EPA)
LC50 Inhalation - Rat - 4 h - > 5,324 mg/l - dust/mist (OECD Test Guideline 403)
LD50 Dermal - Rabbit - > 2,000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
LC50 Inhalation - Rat - 4 h - > 5,324 mg/l - dust/mist (OECD Test Guideline 403)
LD50 Dermal - Rabbit - > 2,000 mg/kg (OECD Test Guideline 402)
Skin - Rabbit
Result: No skin irritation (OECD Test Guideline 404)
Serious eye damage/eye irritation
Result: No skin irritation (OECD Test Guideline 404)
Eyes - Rabbit
Result: Mild eye irritation (OECD Test Guideline 405)
Respiratory or skin sensitization
Result: Mild eye irritation (OECD Test Guideline 405)
Maximization Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Germ cell mutagenicity
Result: negative (OECD Test Guideline 406)
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
May cause damage to organs through prolonged or repeated exposure.
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Aspiration hazard
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified based on available data. For more details, see section 2
11.2 Additional Information
Repeated dose toxicity - Rat - male and female - Oral - 90 d - NOAEL (No observed adverse effect level) - 2 mg/kg
Remarks: Subchronic toxicity
Repeated dose toxicity - Rabbit - female - Dermal - 28 d - NOAEL (No observed adverse effect level) - 0.5 mg/kg
Remarks: Subacute toxicity
RTECS: XY4550000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Remarks: Subchronic toxicity
Repeated dose toxicity - Rabbit - female - Dermal - 28 d - NOAEL (No observed adverse effect level) - 0.5 mg/kg
Remarks: Subacute toxicity
RTECS: XY4550000
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Ecotoxicity
Components:
Terbuthylazine:
Toxicity to fishLC50 (Oncorhynchus mykiss (rainbow trout)): 2.2 mg/l Exposure time: 96 h Test Type: static test Method: OECD Test Guideline 203
Toxicity to daphnia and other aquatic invertebrates
EC50 (Daphnia magna (Water flea)): 11 mg/l Exposure time: 48 h Test Type: static test Method: OECD Test Guideline 202 GLP: yes Remarks: (above the solubility limit in the test medium)
Toxicity to algae/aquatic plants
ErC50 (Pseudokirchneriella subcapitata (green algae)): 0.028 mg/l Exposure time: 72 h Test Type: static test Method: OECD Test Guideline 201 GLP: yes
Ecotoxicology Assessment
Acute aquatic toxicityVery toxic to aquatic life.
Chronic aquatic toxicity
Very toxic to aquatic life with long lasting effects.
Persistence and degradability
Components:
Terbuthylazine:
BiodegradabilityResult: Not readily biodegradable. Biodegradation: 3 - 9 % Exposure time: 28 d Method: OECD Test Guideline 301B
Bioaccumulative potential
Components:
Terbuthylazine:
Partition coefficient: noctanol/waterlog Pow: 3.4 (25 °C) Method: Regulation (EC) No. 440/2008, Annex, A.8 Remarks: Bioaccumulation is not expected.
Mobility in soil
No data available
Other adverse effects
No data available
Disposal methods
Waste from residuesOffer surplus and non-recyclable solutions to a licensed disposal company.
International Regulations
IATA-DGR
UN/ID No. : UN 3077
Proper shipping name : Environmentally hazardous substance, solid, n.o.s.
(Terbuthylazine)
Class : 9
Packing group : III
Labels : Class 9 - Miscellaneous dangerous substances and articles
Packing instruction (cargo aircraft) : 956
Packing instruction (passenger aircraft) : 956
Proper shipping name : Environmentally hazardous substance, solid, n.o.s.
(Terbuthylazine)
Class : 9
Packing group : III
Labels : Class 9 - Miscellaneous dangerous substances and articles
Packing instruction (cargo aircraft) : 956
Packing instruction (passenger aircraft) : 956
IMDG-Code
UN number : UN 3077
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(Terbuthylazine)
Class : 9
Packing group : III
Labels : 9
EmS Code : F-A, S-F
Marine pollutant : yes
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(Terbuthylazine)
Class : 9
Packing group : III
Labels : 9
EmS Code : F-A, S-F
Marine pollutant : yes
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
National regulation GB 6944/12268
UN number : UN 3077
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(Terbuthylazine)
Class : 9
Packing group : III
Labels : 9
National regulation GB 6944/12268
UN number : UN 3077
Proper shipping name : ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(Terbuthylazine)
Class : 9
Packing group : III
Labels : 9
Special precautions for user
Remarks : EHS-Mark required (ADR 2.2.9.1.10, IMDG code 2.10.3) for single packagings and combination packagings containing inner packagings with Dangerous
Goods > 5L for liquids or > 5kg for solids.
Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
Goods > 5L for liquids or > 5kg for solids.
Packages smaller than or equal to 5 kg / L , not dangerous goods of Class 9
The transport classification(s) provided herein are for informational purposes only, and solely based upon the properties of the unpackaged material as it is described within this Safety Data Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations.
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals
Hazardous Chemicals for Priority Management
under SAWS
Regulation of Environmental Management on the First Import of Chemicals and the Import and Export of Toxic Chemicals
China Severely Restricted Toxic Chemicals for Import and Export
Full text of other abbreviations
ACGIHUSA. ACGIH Threshold Limit Values (TLV)
ACGIH / TWA AIIC - Australian Invent Transport by Land of Bra bw - Body weight; CMR Standard of the German List (Canada); ECx - Conc associated with x% respo Chemical Substances (Jap response; ERG - Emerge GLP - Good Laboratory P cer; IATA - International Construction and Equipm Half maximal inhibitory c tion; IECSC - Inventory o tional Maritime Dangerou Industrial Safety and H Standardization; KECI - K tration to 50 % of a test (Median Lethal Dose); MA lution from Ships; n.o.s. No Observed (Adverse) E fect Level; NOELR - No Norm; NTP - National Toxi icals; OECD - Organizatio fice of Chemical Safety a and Toxic substance; PIC stances; (Q)SAR - (Quant (EC) No 1907/2006 of th Registration, Evaluation, Accelerating Decompositi Chemical Substance Inve Thailand Existing Chemica States); UN - United Nat Transport of Dangerous WHMIS - Workplace Hazar
8-hour, time-weighted average ry of Industrial Chemicals
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI - s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
ANTT - National Agency for il
ASTM - American Society for the Testing of Materials
- Carcinogen, Mutagen or Reproductive Toxicant
DIN nstitute for Standardisation
DSL - Domestic Substances ntration associated with x% response
ELx - Loading rate se
EmS - Emergency Schedule
ENCS - Existing and New n)
ErCx - Concentration associated with x% growth rate cy Response Guide
GHS - Globally Harmonized System
actice
IARC - International Agency for Research on Canir Transport Association
IBC - International Code for the nt of Ships carrying Dangerous Chemicals in Bulk
IC50 ncentration
ICAO - International Civil Aviation Organiza- Existing Chemical Substances in China
IMDG - Interna- Goods
IMO - International Maritime Organization
ISHL alth Law (Japan)
ISO - International Organisation for rea Existing Chemicals Inventory
LC50 - Lethal Concenopulation
LD50 - Lethal Dose to 50% of a test population POL - International Convention for the Prevention of Pol- Not Otherwise Specified
Nch - Chilean Norm
NO(A)EC fect Concentration
NO(A)EL - No Observed (Adverse) Efbservable Effect Loading Rate
NOM - Official Mexican ology Program
NZIoC - New Zealand Inventory of Chemfor Economic Co-operation and Development
OPPTS - Ofd Pollution Prevention
PBT - Persistent, Bioaccumulative S - Philippines Inventory of Chemicals and Chemical Subtative) Structure Activity Relationship
REACH - Regulation European Parliament and of the Council concerning the uthorisation and Restriction of Chemicals
SADT - Selfn Temperature
SDS - Safety Data Sheet
TCSI - Taiwan tory
TDG - Transportation of Dangerous Goods
TECI - s Inventory
TSCA - Toxic Substances Control Act (United ons
UNRTDG - United Nations Recommendations on the oods
vPvB - Very Persistent and Very Bioaccumulative
ous Materials Information System
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.