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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >3,3'-Diindolylmethane

3,3'-Diindolylmethane

3,3'-Diindolylmethane Structure
  • ₹2979 - ₹15382.33
  • Product name: 3,3'-Diindolylmethane
  • CAS: 1968-05-4
  • MF: C17H14N2
  • MW: 246.31
  • EINECS:100-201-5
  • MDL Number:MFCD00195766
  • Synonyms:3,3'-Diindolylmethane(DIM);Di(1H-indol-3-yl);Plant Indole;3,3'-DIINDOLYLMETHANE, >=98% (HPLC);3,3'-METHYLENEBIS-1H-INDOLE;3,3'-METHYLENEDIINDOLE;ARUNDINE;BIS(3-INDOLYL)METHANE
Price6 Properties Safety Information Description
6 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 100MG
  • 1gm
  • 5gm
  • 5G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberM1399
  • Product description3,3'-Methylenediindole
  • Packaging5G
  • Price₹5500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM1399
  • Product description3,3'-Methylenediindole
  • Packaging25G
  • Price₹9400
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberD9568
  • Product description3,3′-Diindolylmethane ≥98% (HPLC)
  • Packaging5G
  • Price₹15003.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number74601
  • Product description3,3′-Diindolylmethane analytical standard
  • Packaging100MG
  • Price₹15382.33
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number D 1899
  • Product description3,3-Diindolylmethane, 99%
  • Packaging1gm
  • Price₹2979
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number D 1899
  • Product description3,3-Diindolylmethane, 99%
  • Packaging5gm
  • Price₹12708
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) M1399 3,3'-Methylenediindole 5G ₹5500 2022-05-26 Buy
TCI Chemicals (India) M1399 3,3'-Methylenediindole 25G ₹9400 2022-05-26 Buy
Sigma-Aldrich(India) D9568 3,3′-Diindolylmethane ≥98% (HPLC) 5G ₹15003.45 2022-06-14 Buy
Sigma-Aldrich(India) 74601 3,3′-Diindolylmethane analytical standard 100MG ₹15382.33 2022-06-14 Buy
ottokemi D 1899 3,3-Diindolylmethane, 99% 1gm ₹2979 2022-05-26 Buy
ottokemi D 1899 3,3-Diindolylmethane, 99% 5gm ₹12708 2022-05-26 Buy

Properties

Melting point :167 °C
Boiling point :230 °C(Press: 0.01 Torr)
Density :1.271±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform (Sparingly), Methanol (Slightly)
pka :16.91±0.30(Predicted)
form :Off-white powder.
color :White to Pale Beige
InChI :InChI=1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2
InChIKey :VFTRKSBEFQDZKX-UHFFFAOYSA-N
SMILES :C(C1C2=C(NC=1)C=CC=C2)C1C2=C(NC=1)C=CC=C2
LogP :4.401 (est)
CAS DataBase Reference :1968-05-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

3,3’-Diindolylmethane (DIM) is a bioactive metabolite of indole-3-carbinol, a phytochemical produced by the breakdown of the glucosinolate glucobrassicin found in cruciferous vegetables. At 10-30 μM, it demonstrates anticancer and chemopreventative effects involving Nrf2 induction of Phase 2 enzymes, promotion of apoptosis, induction of cell cycle arrest, inhibition of cell proliferation, and inhibition of histone deacetylases and DNA methylation activities. Furthermore, at 0.3 μM DIM was shown to act as a potent radioprotector and mitigator of the effects of ionizing radiation exposure by stimulating an ATM-driven DNA damage-like response and NF-κB survival signaling in cultured epithelial cells.

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