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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Quinolones >Enoxacin

Enoxacin

Enoxacin Structure
  • ₹0
  • Product name: Enoxacin
  • CAS: 74011-58-8
  • MF: C15H17FN4O3
  • MW: 320.32
  • EINECS:1308068-626-2
  • MDL Number:MFCD00133308
  • Synonyms:1,8-naphthyridine-3-carboxylicacid,1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-pi ;1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-car ;at-2266 ;bactidan ;ci919 ;comprecin ;enoram ;Enoxacine
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :220-224 C
Boiling point :569.9±50.0 °C(Predicted)
Density :1.2931 (estimate)
storage temp. :2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :6.04±0.70(Predicted)
form :Solid
color :Off-White to Pale Yellow
Water Solubility :50 mg/ml in 1 M NaOHSlightly soluble in sodium hydroxide, dimethyl sulfoxide, chloroform and methanol. Insoluble in water.
InChI :InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23)
InChIKey :IDYZIJYBMGIQMJ-UHFFFAOYSA-N
SMILES :N1(CC)C2C(=CC(F)=C(N3CCNCC3)N=2)C(=O)C(C(O)=O)=C1
CAS DataBase Reference :74011-58-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Enoxacin is a fluoroquinolone that prevents bacterial growth by interfering with DNA replication, inhibiting bacterial DNA gyrase (IC50 = 126 μg/ml) and topoisomerase IV (IC50 = 26.5 μg/ml). It demonstrates broad-spectrum antibacterial activity against many Gram-positive and Gram-negative bacteria. Its ability to bind to TAR RNA-binding protein 2, a microRNA biosynthesis protein, has been used to enhance the production of microRNAs with tumor suppressor functions to generate tumor-specific growth inhibitory effects in cancer models.

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Norfloxacin Levofloxacin hydrochloride Ofloxacin Enoxacin Enoxolone 1,8-NAPHTHYRIDINE Hydrogen

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Suppliers and manufacturers

Henan Bao Enluo International TradeCo.，LTD
Enoxacin
₹50.00 /1kg
Enoxacin CAS:74011-58-8
Shaanxi Xianhe Biotech Co., Ltd
Enoxacin
₹0.00 /1KG
Enoxacin CAS:74011-58-8
Pharmaffiliates Analytics and Synthetics P. Ltd Indogulf Group Clearsynth Labs CLEARSYNTH LABS LTD. Pharma Affiliates Maas Pharma Chemicals Samex Overseas
Henan Tianfu Chemical Co.,Ltd.