Miltefosine
|
- ₹4300 - ₹17449.9
- Product name: Miltefosine
- CAS: 58066-85-6
- MF: C21H46NO4P
- MW: 407.57
- EINECS:622-572-6
- MDL Number:MFCD00133396
- Synonyms:2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-n,n,n-trimethyl-ethanaminiuhydrox ;2-(((hexadecyloxy)hydroxyphosphinyl)oxy)-n,n,n-trimethylethanaminiumhydroxid ;cholinephosphate,hexadecylester,hydroxide,innersalt ;d18506 ;Hexadecyl 2-(trimethylamino)ethyl phosphate;Miltex;13-18506;2-[[(Hexadecyloxy)hydroxyphasphinyl]oxy]-N，N，N-trimethylethanaminiminner salt
4 prices
Selected condition：
Brand
- TCI Chemicals (India)
- Sigma-Aldrich(India)
Package
- 50MG
- 100MG
- 1G
- ManufacturerTCI Chemicals (India)
- Product numberM2445
- Product descriptionMiltefosine
- Packaging100MG
- Price₹4300
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberM2445
- Product descriptionMiltefosine
- Packaging1G
- Price₹14700
- Updated2022-05-26
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM5571
- Product descriptionMiltefosine ≥98% (perchloric acid titration)
- Packaging50MG
- Price₹10045.6
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberM5571
- Product descriptionMiltefosine ≥98% (perchloric acid titration)
- Packaging100MG
- Price₹17449.9
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | M2445 | Miltefosine | 100MG | ₹4300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | M2445 | Miltefosine | 1G | ₹14700 | 2022-05-26 | Buy |
| Sigma-Aldrich(India) | M5571 | Miltefosine ≥98% (perchloric acid titration) | 50MG | ₹10045.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M5571 | Miltefosine ≥98% (perchloric acid titration) | 100MG | ₹17449.9 | 2022-06-14 | Buy |
Properties
Melting point :232-234° (dec)
storage temp. :room temp
solubility :H2O: soluble10mg/mL, clear, colorless
form :Crystalline solid
color :White to Almost white
biological source :synthetic (organic)
Water Solubility :H2O: 10mg/mL, clear, colorless
InChI :InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
InChIKey :PQLXHQMOHUQAKB-UHFFFAOYSA-N
SMILES :O(CCCCCCCCCCCCCCCC)P([O-])(=O)OCC[N+](C)(C)C
CAS DataBase Reference :58066-85-6(CAS DataBase Reference)
storage temp. :room temp
solubility :H2O: soluble10mg/mL, clear, colorless
form :Crystalline solid
color :White to Almost white
biological source :synthetic (organic)
Water Solubility :H2O: 10mg/mL, clear, colorless
InChI :InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3
InChIKey :PQLXHQMOHUQAKB-UHFFFAOYSA-N
SMILES :O(CCCCCCCCCCCCCCCC)P([O-])(=O)OCC[N+](C)(C)C
CAS DataBase Reference :58066-85-6(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Miltefosine is an inhibitor of CTP:phosphocholine cytidylyl transferase and has antimetastatic properties. At concentrations of 3 and 25 μM, miltefosine inhibits proliferation of HaCaT cells (immortalized human keratinocyte cell line) by 50% and 94%, respectively. The mechanism of action of miltefosine is not well established, but the antiproliferative effect may be mediated by an increase in cellular ceramide which results in apoptosis. Treatment of cells with 25 μM miltefosine results in a 53% increase in ceramide concentration relative to control. Miltefosine is more than 90% effective in eradicating visceral infections of Leishmania species (kala azar), although the mechanism of this antiprotozoal activity is also poorly understood.Related product price
- 9032-42-2
₹3480-13011.65 - Tylosin phosphate
₹5120.23 - Tributyl phosphate
₹1640-65110.01
