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ChemicalBook > Product Catalogue >API >Antineoplastic agents >Natural sources of antineoplastic >Topotecan

Topotecan

Topotecan Structure
  • ₹8210 - ₹34943.1
  • Product name: Topotecan
  • CAS: 123948-87-8
  • MF: C23H23N3O5
  • MW: 421.45
  • EINECS:687-471-1
  • MDL Number:MFCD00870670
  • Synonyms:1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (S)-;Hycamptin;nogitecan;NSC 609699;SKF 104864;SKF-S 104864;Topotecan lactone;Hydrochloric Acid Solution, 0.02N (N/50)
4 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 1L
  • 1003261003
  • ManufacturerSigma-Aldrich(India)
  • Product number1.00326
  • Product descriptionHydrochloric acid in 2-propanol acc. to DIN 51558 part 1 c(HCl) = 0.1 mol/l (0,1 N), Titripur?
  • Packaging1003261003
  • Price₹8210
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2705
  • Product descriptionTopotecan hydrochloride hydrate ≥98% (HPLC and enzymatic)
  • Packaging10MG
  • Price₹8746.6
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number1.00326
  • Product descriptionHydrochloric acid in 2-propanol acc. to DIN 51558 part 1 c(HCl) = 0.1 mol/l (0,1 N), Titripur?
  • Packaging1L
  • Price₹10930.01
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberT2705
  • Product descriptionTopotecan hydrochloride hydrate ≥98% (HPLC and enzymatic)
  • Packaging50MG
  • Price₹34943.1
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 1.00326 Hydrochloric acid in 2-propanol acc. to DIN 51558 part 1 c(HCl) = 0.1 mol/l (0,1 N), Titripur? 1003261003 ₹8210 2022-06-14 Buy
Sigma-Aldrich(India) T2705 Topotecan hydrochloride hydrate ≥98% (HPLC and enzymatic) 10MG ₹8746.6 2022-06-14 Buy
Sigma-Aldrich(India) 1.00326 Hydrochloric acid in 2-propanol acc. to DIN 51558 part 1 c(HCl) = 0.1 mol/l (0,1 N), Titripur? 1L ₹10930.01 2022-06-14 Buy
Sigma-Aldrich(India) T2705 Topotecan hydrochloride hydrate ≥98% (HPLC and enzymatic) 50MG ₹34943.1 2022-06-14 Buy

Properties

Melting point :−114 °C(lit.)
Boiling point :>100 °C(lit.)
Density :1.2 g/mL at 25 °C(lit.)
vapor density :1.3 (vs air)
vapor pressure :613 psi ( 21.1 °C)
Flash point :12 °C
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :H2O: soluble
form :liquid
pka :8.92±0.40(Predicted)
color :yellow
InChI :InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1
InChIKey :UCFGDBYHRUNTLO-QHCPKHFHSA-N
SMILES :N1C2C(=C(CN(C)C)C(O)=CC=2)C=C2CN3C(C=12)=CC1[C@](CC)(O)C(=O)OCC=1C3=O
CAS DataBase Reference :123948-87-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Topotecan-d6 is a labeled Topotecan. A DNA topoisomerase I inhibitor, a semisynthetic analog of Camptothecin and an antineoplastic.

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