2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-
![2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]- price.](/CAS/GIF/194423-06-8.gif)
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- $37 - $1234
- Product name: 2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-
- CAS: 194423-06-8
- MF: C18H13BrN4O
- MW: 381.23
- EINECS:
- MDL Number:MFCD02179194
- Synonyms:CL-387785 (EKI-785);N-(4-(3-bromophenylamino)quinazolin-6-yl)but-2-ynamide;N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-2-ButynaMide CL-387785;2-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-;CL-387785, >=98%;CL-38875;EKB 785;WAY-EKI 785
37 prices
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Brand
- Activate Scientific
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 10mM(in 1mL DMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerActivate Scientific
- Product numberAS116442
- Product descriptionCL-387785 98+%
- Packaging5mg
- Price$166
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS116442
- Product descriptionCL-387785 98+%
- Packaging25mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS116442
- Product descriptionCL-387785 98+%
- Packaging100mg
- Price$1234
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3554AH
- Product descriptionN-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamide
- Packaging1g
- Price$718
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA119062
- Product descriptionCL-387785 98+%
- Packaging2mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA119062
- Product descriptionCL-387785 98+%
- Packaging5mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA119062
- Product descriptionCL-387785 98+%
- Packaging10mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA119062
- Product descriptionCL-387785 98+%
- Packaging25mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5899
- Product descriptionCL-387785(EKI-785)
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5899
- Product descriptionCL-387785(EKI-785)
- Packaging10mM(in 1mL DMSO)
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5899
- Product descriptionCL-387785(EKI-785)
- Packaging25mg
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5899
- Product descriptionCL-387785(EKI-785)
- Packaging100mg
- Price$685
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS438710
- Product descriptionCL-387785 ≥98%
- Packaging25mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19081
- Product descriptionCL-387785 ≥95%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19081
- Product descriptionCL-387785 ≥95%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19081
- Product descriptionCL-387785 ≥95%
- Packaging10mg
- Price$178
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Activate Scientific | AS116442 | CL-387785 98+% | 5mg | $166 | 2021-12-16 | Buy |
| Activate Scientific | AS116442 | CL-387785 98+% | 25mg | $460 | 2021-12-16 | Buy |
| Activate Scientific | AS116442 | CL-387785 98+% | 100mg | $1234 | 2021-12-16 | Buy |
| AK Scientific | 3554AH | N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamide | 1g | $718 | 2021-12-16 | Buy |
| Ambeed | A119062 | CL-387785 98+% | 2mg | $51 | 2021-12-16 | Buy |
| Ambeed | A119062 | CL-387785 98+% | 5mg | $86 | 2021-12-16 | Buy |
| Ambeed | A119062 | CL-387785 98+% | 10mg | $145 | 2021-12-16 | Buy |
| Ambeed | A119062 | CL-387785 98+% | 25mg | $245 | 2021-12-16 | Buy |
| ApexBio Technology | B5899 | CL-387785(EKI-785) | 5mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | B5899 | CL-387785(EKI-785) | 10mM(in 1mL DMSO) | $90 | 2021-12-16 | Buy |
| ApexBio Technology | B5899 | CL-387785(EKI-785) | 25mg | $275 | 2021-12-16 | Buy |
| ApexBio Technology | B5899 | CL-387785(EKI-785) | 100mg | $685 | 2021-12-16 | Buy |
| Arctom | AS438710 | CL-387785 ≥98% | 25mg | $243 | 2021-12-16 | Buy |
| Cayman Chemical | 19081 | CL-387785 ≥95% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 19081 | CL-387785 ≥95% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 19081 | CL-387785 ≥95% | 10mg | $178 | 2024-03-01 | Buy |
Properties
Melting point :276 °C
Density :1.577±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥16.85 mg/mL in DMSO
pka :9.84±0.43(Predicted)
form :Off-white to yellow solid.
color :White to Orange to Green
Density :1.577±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥16.85 mg/mL in DMSO
pka :9.84±0.43(Predicted)
form :Off-white to yellow solid.
color :White to Orange to Green
Safety Information
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Description
Overactivity of epidermal growth factor receptor (EGFR) tyrosine kinase activity has been associated with a number of cancers. CL-387785 is a potent, irreversible inhibitor of EGFR kinase activity (IC50 = 370 pM). It blocks EGF-stimulated autophosphorylation of receptors in cells (IC50 = 5 nM) and halts cell cycling in cells that overexpress EGFR or c-ErbB2 (IC50s = 31-125 nM). CL-387785 profoundly blocks the growth of EGFR-overexpressing tumors in nude mice when given orally at 80 mg/kg/day for 10 days.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
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![N-[4-(3-bromoanilino)quinazolin-6-yl]but-2-ynamide](https://img.chemicalbook.com/ProductImageEN/2019-12/small/6071f2ba-f93d-486f-9cdb-74f52151c90f.png){kind=small}