ALK5 inhibitor II
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- $26 - $2245.7
- Product name: ALK5 inhibitor II
- CAS: 446859-33-2
- MF: C17H13N5
- MW: 287.32
- EINECS:
- MDL Number:MFCD09037561
- Synonyms:ALK5 INHIBITOR I;2-(3-(6-METHYLPYRIDIN-2-YL)-1H-PYRAZOL-4-YL)-1,5-NAPHTHYRIDINE;2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine;SJN 2511;2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine;E 616452;E616452;1,5-Naphthyridine, 2-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-
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Brand
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 10
- 1mg
- 10mg
- 50
- 5mg
- 25mg
- 50mg
- 100mg
- 250mg
- 10mM(in 1mL DMSO)
- 1000mg
- 1g
- ManufacturerApexBio Technology
- Product numberA3754
- Product descriptionRepSox
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3754
- Product descriptionRepSox
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3754
- Product descriptionRepSox
- Packaging25mg
- Price$165
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60343
- Product descriptionRepSox ≥98%
- Packaging10mg
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546228
- Product descriptionRepSox >98%
- Packaging5mg
- Price$181.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546228
- Product descriptionRepSox >98%
- Packaging25mg
- Price$472.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180865
- Product descriptionRepsox (ALK5 Inhibitor II) >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180865
- Product descriptionRepsox (ALK5 Inhibitor II) >98%
- Packaging250mg
- Price$1133.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180865
- Product descriptionRepsox (ALK5 Inhibitor II) >98%
- Packaging1000mg
- Price$2245.7
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR44793
- Product descriptionRepSox
- Packaging10mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFR44793
- Product descriptionRepSox
- Packaging50mg
- Price$332.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14794
- Product descriptionALK5 Inhibitor II ≥98%
- Packaging1mg
- Price$26
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14794
- Product descriptionALK5 Inhibitor II ≥98%
- Packaging5mg
- Price$65
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14794
- Product descriptionALK5 Inhibitor II ≥98%
- Packaging10mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14794
- Product descriptionALK5 Inhibitor II ≥98%
- Packaging25mg
- Price$255
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1321
- Product descriptionRepSox 99.96%
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | A3754 | RepSox | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A3754 | RepSox | 10mg | $90 | 2021-12-16 | Buy |
| ApexBio Technology | A3754 | RepSox | 25mg | $165 | 2021-12-16 | Buy |
| Arctom | CFN60343 | RepSox ≥98% | 10mg | $208 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546228 | RepSox >98% | 5mg | $181.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546228 | RepSox >98% | 25mg | $472.6 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180865 | Repsox (ALK5 Inhibitor II) >98% | 100mg | $615.4 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180865 | Repsox (ALK5 Inhibitor II) >98% | 250mg | $1133.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180865 | Repsox (ALK5 Inhibitor II) >98% | 1000mg | $2245.7 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR44793 | RepSox | 10mg | $95 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FR44793 | RepSox | 50mg | $332.5 | 2021-12-16 | Buy |
| Cayman Chemical | 14794 | ALK5 Inhibitor II ≥98% | 1mg | $26 | 2024-03-01 | Buy |
| Cayman Chemical | 14794 | ALK5 Inhibitor II ≥98% | 5mg | $65 | 2024-03-01 | Buy |
| Cayman Chemical | 14794 | ALK5 Inhibitor II ≥98% | 10mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 14794 | ALK5 Inhibitor II ≥98% | 25mg | $255 | 2024-03-01 | Buy |
| ChemScene | CS-1321 | RepSox 99.96% | 5mg | $70 | 2021-12-16 | Buy |
Properties
Melting point :195 °C
Boiling point :501.9±50.0 °C(Predicted)
Density :1.296±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :Yellow solid
pka :10.05±0.50(Predicted)
color :Pale yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :LBPKYPYHDKKRFS-UHFFFAOYSA-N
Boiling point :501.9±50.0 °C(Predicted)
Density :1.296±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :Yellow solid
pka :10.05±0.50(Predicted)
color :Pale yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChIKey :LBPKYPYHDKKRFS-UHFFFAOYSA-N
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
ALK5 inhibitor II is a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-β cellular assay, and ALK5 binding in HepG2 cells, respectively). This inhibitor demonstrated less potent activity (IC50s > 16 μM) when tested against a panel of 9 related kinases, including p38 MAPK and GSK3. At 25 μM, this compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription.More related product prices
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$28-2245.7
