AZ191
|
- $30 - $2100
- Product name: AZ191
- CAS: 1594092-37-1
- MF: C24H27N7O
- MW: 429.52
- EINECS:
- MDL Number:MFCD28015098
- Synonyms:N-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1h-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine, AZ191;[2-Methoxy-4-(4-methyl-piperazin-1-yl)-phenyl]-[4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-pyrimidin-2-yl]-amine;AZ191;AZ-191;AZ 191;CS-1824;N-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1h-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinamine;2-Pyrimidinamine, N-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-4-(1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-;Inhibitor,AZ-191,Dual specificity tyrosine regulated kinase,AZ191,Dual specificity tyrosine phosphorylation regulated kinase,inhibit,AZ 191,DYRK
51 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- Ambeed
- ApexBio Technology
- Arctom
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Tocris
- TRC
Package
- 5.00mg
- 10.00mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 250mg
- 50
- 25.00mg
- 10
- 1g
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mM(in1mLDMSO)
- 5mg
- 10mg
- 25mg
- 100MG
- 10mM(1mLinDMSO)
- 50mg
- Manufactureraablocks
- Product numberAA00ABFX
- Product descriptionAZ 191 ≥98%
- Packaging1mg
- Price$36
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABFX
- Product descriptionAZ 191 99%
- Packaging5mg
- Price$47
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABFX
- Product descriptionAZ 191 99%
- Packaging10mg
- Price$69
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABFX
- Product descriptionAZ 191 99%
- Packaging25mg
- Price$106
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ABFX
- Product descriptionAZ 191 99%
- Packaging50mg
- Price$138
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberT94545
- Product descriptionAZ191 98%
- Packaging25MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT94545
- Product descriptionAZ191 98%
- Packaging100MG
- Price$285
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3657-M025
- Product descriptionAZ191 ≥98%
- Packaging25mg
- Price$190
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3657-M001
- Product descriptionAZ191 ≥98%
- Packaging1mg
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3657-M005
- Product descriptionAZ191 ≥98%
- Packaging5mg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberY1892
- Product descriptionAZ191
- Packaging5mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY1892
- Product descriptionAZ191
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA404720
- Product descriptionAz191 98+%
- Packaging10mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA404720
- Product descriptionAz191 98+%
- Packaging5mg
- Price$82
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA404720
- Product descriptionAz191 98+%
- Packaging1mg
- Price$37
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1890
- Product descriptionAZ191
- Packaging10mM(in1mLDMSO)
- Price$83
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ABFX | AZ 191 ≥98% | 1mg | $36 | 2026-05-28 | Buy |
| aablocks | AA00ABFX | AZ 191 99% | 5mg | $47 | 2026-05-28 | Buy |
| aablocks | AA00ABFX | AZ 191 99% | 10mg | $69 | 2026-05-28 | Buy |
| aablocks | AA00ABFX | AZ 191 99% | 25mg | $106 | 2026-05-28 | Buy |
| aablocks | AA00ABFX | AZ 191 99% | 50mg | $138 | 2026-05-28 | Buy |
| ACHEMBLOCK | T94545 | AZ191 98% | 25MG | $110 | 2026-05-27 | Buy |
| ACHEMBLOCK | T94545 | AZ191 98% | 100MG | $285 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CR1-3657-M025 | AZ191 ≥98% | 25mg | $190 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3657-M001 | AZ191 ≥98% | 1mg | $30 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3657-M005 | AZ191 ≥98% | 5mg | $80 | 2026-05-06 | Buy |
| AK Scientific | Y1892 | AZ191 | 5mg | $218 | 2021-12-16 | Buy |
| AK Scientific | Y1892 | AZ191 | 1mg | $133 | 2021-12-16 | Buy |
| Ambeed | A404720 | Az191 98+% | 10mg | $122 | 2021-12-16 | Buy |
| Ambeed | A404720 | Az191 98+% | 5mg | $82 | 2021-12-16 | Buy |
| Ambeed | A404720 | Az191 98+% | 1mg | $37 | 2021-12-16 | Buy |
| ApexBio Technology | B1890 | AZ191 | 10mM(in1mLDMSO) | $83 | 2026-05-06 | Buy |
Properties
Boiling point :705.3±70.0 °C(Predicted)
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :7.76±0.42(Predicted)
color :white to yellow to light brown
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :7.76±0.42(Predicted)
color :white to yellow to light brown
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (DYRK1B) belongs to a family of nuclear-localized protein kinases and participates in the regulation of the cell cycle with key roles in proliferation and differentiation. It is upregulated in solid tumors and gain-of-function mutations in the gene encoding this kinase have been linked to metabolic syndrome. AZ191 is a cell-permeable azaindole that inhibits the serine/threonine kinase activity of DYRK1B (IC50 = 17 nM) with 5-fold and 110-fold selectivity against the related family members DYRK1A and DYRK2, respectively. This compound has been used as a probe to elucidate the mechanism of DYRK1B regulation of cell cycle progression.{28993Related product price
-
BI-D1870
$57-4966.5 -
Temozolomide
$5-2935 -
MG-132
$11-9807.9
Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
Chembest Research Laboratories Limited
Haoyuan Chemexpress Co., Ltd.
AdooQ BioScience, LLC
Bide Pharmatech Ltd.
ShangHai KenEn Chemical Technology Co., Ltd.
Shanghai Qinghang Chemical Co. Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
Tongling HengYou Biotechnology Co., Ltd.
YouCoChem (Beijing) Chemical Technology Co., Ltd.