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ChemicalBook >> CAS DataBase List >> Abacavir-d4

Abacavir-d4

Abacavir-d4 price.
  • $117 - $2194.5
  • Product name: Abacavir-d4
  • CAS: 1260619-56-4
  • MF: C14H18N6O
  • MW: 286.33232
  • EINECS:
  • MDL Number:MFCD11977959
  • Synonyms:(1S,4R)-4-[2-Amino-6-[(cyclopropyl-d4)amino]-9H-purin-9-yl]-2-cycpentene-1-methanol;Abacavir-d4;Ziagen-d4;(1S,4R)-4-[2-AMino-6-(cyclopropylaMino-d4)-9H-purin-9-yl]-2-cyclopentene-1-Methanol;(1S-cis)-4-[2-AMino-6-(cyclopropylaMino-d4)-9H-purin-9-yl]-2-cyclopentene- 1-Methanol;1592U89-d4;ABC-d4;Abacavir-d4
7 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • Usbiological
Package
  • 500μg
  • 1mg
  • 10MG
  • ManufacturerAK Scientific
  • Product number7524DG
  • Product descriptionAbacavir-d4
  • Packaging1mg
  • Price$344
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0006640
  • Product descriptionABACAVIR-D4 95.00%
  • Packaging10MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0006640
  • Product descriptionABACAVIR-D4 95.00%
  • Packaging1MG
  • Price$779.63
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number30076
  • Product descriptionAbacavir-d4
  • Packaging500μg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number30076
  • Product descriptionAbacavir-d4
  • Packaging1mg
  • Price$222
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product numberD6001
  • Product descriptionAbacavir-d4
  • Packaging1mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number001009
  • Product descriptionAbacavir-d4
  • Packaging1mg
  • Price$496
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7524DG Abacavir-d4 1mg $344 2021-12-16 Buy
American Custom Chemicals Corporation RDL0006640 ABACAVIR-D4 95.00% 10MG $2194.5 2021-12-16 Buy
American Custom Chemicals Corporation RDL0006640 ABACAVIR-D4 95.00% 1MG $779.63 2021-12-16 Buy
Cayman Chemical 30076 Abacavir-d4 500μg $117 2024-03-01 Buy
Cayman Chemical 30076 Abacavir-d4 1mg $222 2024-03-01 Buy
Medical Isotopes, Inc. D6001 Abacavir-d4 1mg $390 2021-12-16 Buy
Usbiological 001009 Abacavir-d4 1mg $496 2021-12-16 Buy

Properties

Melting point :222-225°C
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
color :Off-White to Light Beige
Stability :Very Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Abacavir-d4 is intended for use as an internal standard for the quantification of abacavir by GC- or LC-MS. Abacavir is a nucleoside analog and an inhibitor of HIV-1 reverse transcriptase (Ki = 2.1 μM for the wild-type enzyme). It inhibits replication of a variety of HIV-1 and HIV-2 strains, including strains resistant to 3''-azido-3''-deoxythymidine (zidovudine; ) or 2'',3''-dideoxyinosine (didanosine; ), in HeLa cells stably expressing CD4 (IC50s = 5.8-21 μM). Abacavir inhibits replication of eight HIV-1 clinical isolates in phytohemagglutinin-stimulated isolated human peripheral blood lymphocytes with a mean IC50 value of 0.26 μM. It inhibits hepatitis B virus (HBV) DNA synthesis in HepG2 cells (IC50 = 7 μM) and is also active against human cytomegalovirus (CMV) strain AD169 and the Petaluma strain of feline immunodeficiency virus (FIV) in plaque reduction assays (IC50s = 32 and 0.4 μM, respectively). Formulations containing abacavir have been used in the treatment of HIV infection.

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