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ChemicalBook >> CAS DataBase List >> Ametantrone

Ametantrone

Ametantrone price.
  • $44 - $1780.8
  • Product name: Ametantrone
  • CAS: 64862-96-0
  • MF: C22H28N4O4
  • MW: 412.48
  • EINECS:
  • MDL Number:MFCD00723741
  • Synonyms:Ametantrone;1,4-Bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthraquinone;HAQ;NSC-287513;NSC 196473;NSC 290813;AMetantrone(NSC 196473);1,4-BIS(2-(2-HYDROXYETHYLAMINO)ETHYLAMINO)ANTHRACENE-9,10-DIOL
13 prices
Selected condition:
Brand
  • AK Scientific
  • Alichem
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
Package
  • 1mg
  • 5MG
  • 10mg
  • 0.1G
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0251CA
  • Product descriptionAmetantrone
  • Packaging1mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number64862960
  • Product description1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione
  • Packaging100mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number64862960
  • Product description1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione
  • Packaging250mg
  • Price$719.04
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number64862960
  • Product description1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione
  • Packaging1g
  • Price$1780.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009086
  • Product descriptionAMETANTRONE 95.00%
  • Packaging5MG
  • Price$401.43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0009086
  • Product descriptionAMETANTRONE 95.00%
  • Packaging0.1G
  • Price$489.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number22924
  • Product descriptionAmetantrone
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22924
  • Product descriptionAmetantrone
  • Packaging5mg
  • Price$183
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22924
  • Product descriptionAmetantrone
  • Packaging10mg
  • Price$341
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12047368
  • Product description1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione 90%
  • Packaging100mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12047368
  • Product description1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione 90%
  • Packaging1g
  • Price$1680
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7356
  • Product descriptionAmetantrone >98%
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7356
  • Product descriptionAmetantrone >98%
  • Packaging1g
  • Price$1600
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0251CA Ametantrone 1mg $147 2021-12-16 Buy
Alichem 64862960 1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione 100mg $420 2021-12-16 Buy
Alichem 64862960 1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione 250mg $719.04 2021-12-16 Buy
Alichem 64862960 1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione 1g $1780.8 2021-12-16 Buy
American Custom Chemicals Corporation API0009086 AMETANTRONE 95.00% 5MG $401.43 2021-12-16 Buy
American Custom Chemicals Corporation API0009086 AMETANTRONE 95.00% 0.1G $489.5 2021-12-16 Buy
Cayman Chemical 22924 Ametantrone 1mg $44 2024-03-01 Buy
Cayman Chemical 22924 Ametantrone 5mg $183 2024-03-01 Buy
Cayman Chemical 22924 Ametantrone 10mg $341 2024-03-01 Buy
Crysdot CD12047368 1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione 90% 100mg $420 2021-12-16 Buy
Crysdot CD12047368 1,4-Bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione 90% 1g $1680 2021-12-16 Buy
DC Chemicals DC7356 Ametantrone >98% 100mg $400 2021-12-16 Buy
DC Chemicals DC7356 Ametantrone >98% 1g $1600 2021-12-16 Buy

Properties

Melting point :156-158 °C
Boiling point :531.92°C (rough estimate)
Density :1.2344 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :14.47±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Ametantrone is an inhibitor of topoisomerase II. It induces double-strand breaks in SV40 DNA in the presence, but not absence, of topoisomerase II and induces single-strand breaks in DNA in NCI H187 cells. It also induces interstrand DNA cross-links in HeLa S3 cells at a minimum concentration of 4.1 μM. Ametantrone is cytotoxic to NCI H187 and HL-60 cells (IC50s = 112 and 0.44 μM, respectively). It inhibits tumor growth in a Ridgway osteogenic sarcoma mouse model when administered at a dose of 5 mg/kg, however, it increases tumor growth in mouse models of mammary adenocarcinoma and colon adenocarcinoma 11a.

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