Apremilast
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- $13 - $1538
- Product name: Apremilast
- CAS: 608141-41-9
- MF: C22H24N2O7S
- MW: 460.5
- EINECS:807-237-6
- MDL Number:MFCD18782607
- Synonyms:(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide;ApreMilast,CC-10004;AcetaMide, N-[2-[(1S)-1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Apremilast (CC-10004;(S)-N-(2-(1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl);Apremilast (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione;Appleton West;N-[2-[(1S)-1-(3ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide
66 prices
Selected condition：
Brand
- aablocks
- AccelPharmtech
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Labseeker
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 10mM*1mLinDMSO
- 200mg
- 250mg
- 500mg
- 1.00g
- 1000mg
- 10mM(in 1mL DMSO)
- 1g
- 2.5g
- 5g
- 25.00g
- 10mM(in1mLDMSO)
- 5.00g
- 10g
- 25g
- 50g
- 100g
- 250g
- 1 unit
- 10 mg
- 50 mg
- Manufactureraablocks
- Product numberAA0039LL
- Product description(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 97%
- Packaging1g
- Price$29
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039LL
- Product description(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 98%
- Packaging5g
- Price$52
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039LL
- Product description(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 98%
- Packaging25g
- Price$195
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039LL
- Product description(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione ≥99%
- Packaging250mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039LL
- Product description(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 98%
- Packaging2mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0039LL
- Product description(S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 98%
- Packaging1mg
- Price$13
- Updated2026-05-28
- Buy
- ManufacturerAccelPharmtech
- Product numberXP2469
- Product descriptionApremilast 99.00%
- Packaging25G
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerAccelPharmtech
- Product numberXP2469
- Product descriptionApremilast 99.00%
- Packaging5G
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product number10268
- Product descriptionApremilast 98%
- Packaging25G
- Price$260
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10268
- Product descriptionApremilast 98%
- Packaging1G
- Price$20
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10268
- Product descriptionApremilast 98%
- Packaging5G
- Price$65
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0437
- Product descriptionApremilast
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4317
- Product descriptionApremilast (CC-10004)
- Packaging25mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4317
- Product descriptionApremilast (CC-10004)
- Packaging50mg
- Price$143
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4317
- Product descriptionApremilast(CC-10004)
- Packaging10mM(in 1mL DMSO)
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4317
- Product descriptionApremilast (CC-10004)
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0039LL | (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 97% | 1g | $29 | 2026-05-28 | Buy |
| aablocks | AA0039LL | (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 98% | 5g | $52 | 2026-05-28 | Buy |
| aablocks | AA0039LL | (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 98% | 25g | $195 | 2026-05-28 | Buy |
| aablocks | AA0039LL | (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione ≥99% | 250mg | $17 | 2026-05-28 | Buy |
| aablocks | AA0039LL | (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 98% | 2mg | $16 | 2026-05-28 | Buy |
| aablocks | AA0039LL | (S)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione 98% | 1mg | $13 | 2026-05-28 | Buy |
| AccelPharmtech | XP2469 | Apremilast 99.00% | 25G | $260 | 2021-12-16 | Buy |
| AccelPharmtech | XP2469 | Apremilast 99.00% | 5G | $120 | 2021-12-16 | Buy |
| ACHEMBLOCK | 10268 | Apremilast 98% | 25G | $260 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10268 | Apremilast 98% | 1G | $20 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10268 | Apremilast 98% | 5G | $65 | 2026-05-27 | Buy |
| AK Scientific | Y0437 | Apremilast | 10mg | $108 | 2021-12-16 | Buy |
| ApexBio Technology | A4317 | Apremilast (CC-10004) | 25mg | $110 | 2026-05-06 | Buy |
| ApexBio Technology | A4317 | Apremilast (CC-10004) | 50mg | $143 | 2026-05-06 | Buy |
| ApexBio Technology | A4317 | Apremilast(CC-10004) | 10mM(in 1mL DMSO) | $180 | 2021-12-16 | Buy |
| ApexBio Technology | A4317 | Apremilast (CC-10004) | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
Properties
Melting point :152-156°C
Boiling point :741.3±60.0 °C(Predicted)
Density :1.381
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka :14.01±0.20(Predicted)
form :Solid
color :White to Pale Yellow
InChI :1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
InChIKey :IMOZEMNVLZVGJZ-QGZVFWFLSA-N
SMILES :C(NC1=CC=CC2=C1C(=O)N([C@@H](C1=CC=C(OC)C(OCC)=C1)CS(C)(=O)=O)C2=O)(=O)C
CAS DataBase Reference :608141-41-9
Boiling point :741.3±60.0 °C(Predicted)
Density :1.381
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka :14.01±0.20(Predicted)
form :Solid
color :White to Pale Yellow
InChI :1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1
InChIKey :IMOZEMNVLZVGJZ-QGZVFWFLSA-N
SMILES :C(NC1=CC=CC2=C1C(=O)N([C@@H](C1=CC=C(OC)C(OCC)=C1)CS(C)(=O)=O)C2=O)(=O)C
CAS DataBase Reference :608141-41-9
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | ||||||||||||||||||||||
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Description
Apremilast (Otezla) was approved by the FDA on March 21, 2014 for the treatment of adult patients with active psoriatic arthritis. Apremilast is a member of a new class of oral small molecule inhibitors of the phosphosphodiesterase 4 (PDE4) enzyme. When PDE4 is inhibited in immune cells, it results in elevation of intracellular cyclic adenosine monophosphate (cAMP) levels, which can regulate inflammatory mediators. The current clinical data indicate that apremilast is an effective and well tolerated option for the management of psoriasis and PsA in adults.More related product prices
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