| Chemical Properties | Back Directory | [Boiling point ]
761.6±60.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
DMSO: soluble | [form ]
solid | [pka]
8.18±0.60(Predicted) | [InChIKey]
VKLVUAHQOFDKLR-UHFFFAOYSA-N | [SMILES]
O=C1NC(=O)C(c2cn(CCCN3CCNCC3)c4ccccc24)=C1c5c[nH]c6ccccc56 |
| Hazard Information | Back Directory | [Uses]
Bisindolylmaleimide VII is a potent inhibitor of calmodulin with high affinity for calmodulin (Kd=186.2 nM). Bisindolylmaleimide VII is used to study the role of calmodulin in cancer, neurodegenerative diseases, and muscle dysfunction[1]. | [Biological Activity]
Selective inhibitor of protein kinase C. | [References]
[1] Sosa-Peinado, et al. Bisindolylmaleimides new ligands of CaM Protein. Molecules 27.21 (2022): 7161. DOI:10.3390/molecules27217161 |
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