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ChemicalBook >> CAS DataBase List >> Enoxolone

Enoxolone

Enoxolone price.
  • $22 - $196
  • Product name: Enoxolone
  • CAS: 471-53-4
  • MF: C30H46O4
  • MW: 470.68
  • EINECS:207-444-6
  • MDL Number:MFCD00003706
  • Synonyms:3.beta.-Hydroxy-11-oxo-12-oleanen-30-oicacid ;3-beta-hydroxy-11-oxo-olean-12-en-30-oicaci ;3-beta-hydroxy-11-oxoolean-12-en-30-oicacid ;3-hydroxy-11-oxo-,(3.beta.,20.beta.)-Olean-12-en-29-oicacid ;3-hydroxy-11-oxo-,(3beta,20beta)-olean-12-en-29-oicaci ;3-Hydroxy-11-oxo-12-oleanen-30-oicacid ;3BETA-HYDROXY-11-OXO-18BETA, 20BETA-OLEAN-12-EN-29-OIC ACID;3BETA-HYDROXY-11-OXO-18BETA-OLEAN-12-EN-30-OIC ACID
8 prices
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Brand

  • Cayman Chemical
  • Sigma-Aldrich
  • TCI Chemical

Package

  • e0180500
  • 1g
  • 5g
  • 10g
  • 25g
  • ManufacturerCayman Chemical
  • Product number11845
  • Product descriptionβ-Glycyrrhetinic Acid ≥98%
  • Packaging1g
  • Price$25
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number11845
  • Product descriptionβ-Glycyrrhetinic Acid ≥98%
  • Packaging5g
  • Price$48
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number11845
  • Product descriptionβ-Glycyrrhetinic Acid ≥98%
  • Packaging10g
  • Price$88
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG10105
  • Product description18β-Glycyrrhetinic acid 97%
  • Packaging10g
  • Price$105
  • Updated2018-11-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberE0180500
  • Product descriptionEnoxolone European Pharmacopoeia (EP) Reference Standard
  • Packaginge0180500
  • Price$179
  • Updated2018-11-23
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberG10105
  • Product description18β-Glycyrrhetinic acid 97%
  • Packaging25g
  • Price$196
  • Updated2018-11-20
  • Buy
  • ManufacturerTCI Chemical
  • Product numberG0149
  • Product descriptionGlycyrrhetic Acid >97.0%(T)
  • Packaging1g
  • Price$22
  • Updated2018-11-22
  • Buy
  • ManufacturerTCI Chemical
  • Product numberG0149
  • Product descriptionGlycyrrhetic Acid >97.0%(T)
  • Packaging25g
  • Price$173
  • Updated2018-11-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 11845 β-Glycyrrhetinic Acid ≥98% 1g $25 2018-11-13 Buy
Cayman Chemical 11845 β-Glycyrrhetinic Acid ≥98% 5g $48 2018-11-13 Buy
Cayman Chemical 11845 β-Glycyrrhetinic Acid ≥98% 10g $88 2018-11-13 Buy
Sigma-Aldrich G10105 18β-Glycyrrhetinic acid 97% 10g $105 2018-11-20 Buy
Sigma-Aldrich E0180500 Enoxolone European Pharmacopoeia (EP) Reference Standard e0180500 $179 2018-11-23 Buy
Sigma-Aldrich G10105 18β-Glycyrrhetinic acid 97% 25g $196 2018-11-20 Buy
TCI Chemical G0149 Glycyrrhetic Acid >97.0%(T) 1g $22 2018-11-22 Buy
TCI Chemical G0149 Glycyrrhetic Acid >97.0%(T) 25g $173 2018-11-22 Buy

Properties

Melting point: :292-295 °C(lit.)
alpha  :165 º (c=1, CHCl3,on dry ba)
Boiling point: :492.11°C (rough estimate)
Density  :0.9967 (rough estimate)
refractive index  :162 ° (C=1, MeOH)
solubility  :Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.
pka :pKa 5.56±0.1 (Uncertain)
form  :Crystalline Powder
color  :White to off-white
optical activity :[α]22/D +170.0°, c = 1 in chloroform
Water Solubility  :SOLUBLE IN ACETIC ACID
Merck  :14,3590
BRN  :2229654
CAS DataBase Reference :471-53-4(CAS DataBase Reference)
EPA Substance Registry System :Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3.beta.,20.beta.)-(471-53-4)

Safety Information

Symbol(GHS):
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Description

β-Glycyrrhetinic acid is a major metabolite of glycyrrhizin, one of the main constituents of licorice. Both β-glycyrrhetinic acid and glycyrrhizin have been shown to exhibit antiulcerative, anti-inflammatory, and immunomodulatory properties. β-Glycyrrhetinic acid is an inhibitor of the complement pathway (IC50 = 35 μM). At 100 mg/kg/day, β-glycyrrhetinic acid is protective against diabetes complications by reducing lipid peroxidation and increasing antioxidant activity in diabetic rats. β-Glycyrrhetinic acid inhibits mammalian DNA polymerases α, γ, κ, and λ with IC50 values of 16.1, 19.3, 15.8, and 13.7 μM, respectively. At 100-200 μM, β-glycyrrhetinic acid suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages.

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