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ChemicalBook >> CAS DataBase List >> Eprosartan mesylate

Eprosartan mesylate

Eprosartan mesylate price.
  • $5 - $960
  • Product name: Eprosartan mesylate
  • CAS: 144143-96-4
  • MF: C24H28N2O7S2
  • MW: 520.62
  • EINECS:658-063-0
  • MDL Number:MFCD08141807
  • Synonyms:Eprosartan mesylate, >=99%;(E)-4-((2-butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-enyl)-1H-imidazol-1-yl)methyl)benzoic acid;Eprosartan Myslate;4-[[2-butyl-5-(2-carboxy-3-thiophen-2-yl-prop-1-enyl)-imidazol-1-yl]methyl]benzoic acid mesylate;EPROSARTAN MESYLATE;4-({2-butyl-5-[(1E)-2-carboxy-2-(thiophen-2-ylMethyl)eth-1-en-1-yl]-1H-iMidazol-1-yl}Methyl)benzoic acid;(E)-α-[[2-Butyl-1-[(4-carboxyphenyl)Methyl]-1H-iMidazol-5-yl]Methylene]-2-thiophenepropanoic Acid Methanesulfonate;(αE)-α-[[2-Butyl-1-[(4-carboxyphenyl)Methyl]-1H-iMidazol-5-yl]Methylene]-2-thiophenepropanoic Acid MonoMethanesulfonate
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  • 25mg
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  • 10mM(in 1mL DMSO)
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  • 1g
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  • ManufacturerAK Scientific
  • Product numberJ11718
  • Product descriptionEprosartan mesylate
  • Packaging100mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ54813
  • Product descriptionEprosartan mesylate
  • Packaging5g
  • Price$300
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberO812
  • Product descriptionEprosartan mesylate
  • Packaging5g
  • Price$401
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA217175
  • Product description(E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+%
  • Packaging10mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA217175
  • Product description(E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+%
  • Packaging50mg
  • Price$7
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA217175
  • Product description(E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+%
  • Packaging100mg
  • Price$9
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA217175
  • Product description(E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+%
  • Packaging1g
  • Price$31
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA217175
  • Product description(E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+%
  • Packaging5g
  • Price$104
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA217175
  • Product description(E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+%
  • Packaging25g
  • Price$411
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1746
  • Product descriptionEprosartan mesylate
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1746
  • Product descriptionEprosartan mesylate
  • Packaging50mg
  • Price$68
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2485
  • Product descriptionEprosartan Mesylate
  • Packaging25mg
  • Price$49
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2485
  • Product descriptionEprosartan Mesylate
  • Packaging100mg
  • Price$89
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2485
  • Product descriptionEprosartan Mesylate
  • Packaging1g
  • Price$169
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number2485
  • Product descriptionEprosartan Mesylate
  • Packaging10g
  • Price$960
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11578
  • Product descriptionEprosartan (mesylate) ≥98%
  • Packaging10mg
  • Price$50
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J11718 Eprosartan mesylate 100mg $147 2021-12-16 Buy
AK Scientific J54813 Eprosartan mesylate 5g $300 2021-12-16 Buy
AK Scientific O812 Eprosartan mesylate 5g $401 2021-12-16 Buy
Ambeed A217175 (E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+% 10mg $5 2021-12-16 Buy
Ambeed A217175 (E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+% 50mg $7 2021-12-16 Buy
Ambeed A217175 (E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+% 100mg $9 2021-12-16 Buy
Ambeed A217175 (E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+% 1g $31 2021-12-16 Buy
Ambeed A217175 (E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+% 5g $104 2021-12-16 Buy
Ambeed A217175 (E)-4-((2-Butyl-5-(2-carboxy-3-(thiophen-2-yl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoicacidcompoundwithmethanesulfonicacid(1:1) 99+% 25g $411 2021-12-16 Buy
ApexBio Technology B1746 Eprosartan mesylate 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1746 Eprosartan mesylate 50mg $68 2021-12-16 Buy
AvaChem 2485 Eprosartan Mesylate 25mg $49 2021-12-16 Buy
AvaChem 2485 Eprosartan Mesylate 100mg $89 2021-12-16 Buy
AvaChem 2485 Eprosartan Mesylate 1g $169 2021-12-16 Buy
AvaChem 2485 Eprosartan Mesylate 10g $960 2021-12-16 Buy
Cayman Chemical 11578 Eprosartan (mesylate) ≥98% 10mg $50 2024-03-01 Buy

Properties

Melting point :248-250°
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: >10mg/mL
form :powder
color :white to off-white
Merck :14,3635
InChIKey :DJSLTDBPKHORNY-XMMWENQYSA-N
CAS DataBase Reference :144143-96-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Angiotensin II, as part of the renin-angiotensin-aldosterone system, facilitates a sympathetic nervous system response mediated by the angiotensin II type 1 (AT1) receptor, causing vasoconstriction and subsequent increase in blood pressure. It potentiates noradrenaline release from sympathetic nerve terminals at the presynaptic level as well as amplifies the α-adrenoceptor-mediated vasoconstrictor response to endogenous noradrenaline. Angiotensin II receptor blockers (ARBs) are a major class of therapeutics designed to lower blood pressure and to provide cardiovascular protection. Eprosartan (mesylate) is a competitive AT1 receptor antagonist with IC50 values ranging from 1.4 – 3.9 nM and an elimination half-life of five to seven hours. Eprosartan is structurally distinct from other noncompetitive ARBs in that it does not contain a biphenyl, tetrazole moiety and blocks angiotensin II receptors on both sympathetic nerve terminals and blood vessels.

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