KGN
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- $10 - $2610
- Product name: KGN
- CAS: 4727-31-5
- MF: C20H15NO3
- MW: 317.34
- EINECS:
- MDL Number:MFCD00560510
- Synonyms:2-[([1,1'-Biphenyl]-4-ylaMino)carbonyl]benzoic Acid;2-[(Biphenyl-4-yl)carbaMoyl]benzoic Acid;Kartogenin(KGN);4'-Phenylphthalanilic Acid;Kartogenin;KGN;4′-Phenyl-phthalanilic acid (8CI);n-Biphenyl-4-yl-phthalamic acid
41 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Axon Medchem
- BroadPharm
- Cayman Chemical
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 10
- 25mg
- 50mg
- 250mg
- 500mg
- 100mg
- 50
- 1g
- 5g
- 10g
- 25 mg
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number6433AB
- Product description2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoicacid
- Packaging10mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6433AB
- Product description2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoicacid
- Packaging250mg
- Price$253
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6433AB
- Product description2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoicacid
- Packaging5g
- Price$1530
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6433AB
- Product description2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoicacid
- Packaging10g
- Price$2423
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA305493
- Product descriptionKartogenin 98+%
- Packaging1mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA305493
- Product descriptionKartogenin 98+%
- Packaging5mg
- Price$22
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA305493
- Product descriptionKartogenin 98+%
- Packaging10mg
- Price$33
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA305493
- Product descriptionKartogenin 98+%
- Packaging100mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA305493
- Product descriptionKartogenin 98+%
- Packaging250mg
- Price$207
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA305493
- Product descriptionKartogenin 98+%
- Packaging1g
- Price$535
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5626
- Product descriptionKartogenin
- Packaging10mM(in 1mL DMSO)
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5626
- Product descriptionKartogenin
- Packaging10mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5626
- Product descriptionKartogenin
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2378
- Product descriptionKartogenin-KGN 99%
- Packaging10mg
- Price$82.5
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-21555
- Product descriptionN-Biphenyl-4-yl-phthalamicacid
- Packaging250mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-21555
- Product descriptionN-Biphenyl-4-yl-phthalamicacid
- Packaging500mg
- Price$540
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6433AB | 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoicacid | 10mg | $104 | 2021-12-16 | Buy |
| AK Scientific | 6433AB | 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoicacid | 250mg | $253 | 2021-12-16 | Buy |
| AK Scientific | 6433AB | 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoicacid | 5g | $1530 | 2021-12-16 | Buy |
| AK Scientific | 6433AB | 2-([1,1'-Biphenyl]-4-ylcarbamoyl)benzoicacid | 10g | $2423 | 2021-12-16 | Buy |
| Ambeed | A305493 | Kartogenin 98+% | 1mg | $10 | 2021-12-16 | Buy |
| Ambeed | A305493 | Kartogenin 98+% | 5mg | $22 | 2021-12-16 | Buy |
| Ambeed | A305493 | Kartogenin 98+% | 10mg | $33 | 2021-12-16 | Buy |
| Ambeed | A305493 | Kartogenin 98+% | 100mg | $124 | 2021-12-16 | Buy |
| Ambeed | A305493 | Kartogenin 98+% | 250mg | $207 | 2021-12-16 | Buy |
| Ambeed | A305493 | Kartogenin 98+% | 1g | $535 | 2021-12-16 | Buy |
| ApexBio Technology | B5626 | Kartogenin | 10mM(in 1mL DMSO) | $60 | 2021-12-16 | Buy |
| ApexBio Technology | B5626 | Kartogenin | 10mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | B5626 | Kartogenin | 50mg | $250 | 2021-12-16 | Buy |
| Axon Medchem | Axon2378 | Kartogenin-KGN 99% | 10mg | $82.5 | 2021-12-16 | Buy |
| BroadPharm | BP-21555 | N-Biphenyl-4-yl-phthalamicacid | 250mg | $280 | 2021-12-16 | Buy |
| BroadPharm | BP-21555 | N-Biphenyl-4-yl-phthalamicacid | 500mg | $540 | 2021-12-16 | Buy |
Properties
Melting point :272 °C
Boiling point :464.4±38.0 °C(Predicted)
Density :1.289±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >15mg/mL
form :powder
pka :3.45±0.36(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
InChIKey :SLUINPGXGFUMLL-UHFFFAOYSA-N
SMILES :O=C(NC1=CC=C(C2=CC=CC=C2)C=C1)C(C=CC=C3)=C3C(O)=O
Boiling point :464.4±38.0 °C(Predicted)
Density :1.289±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: >15mg/mL
form :powder
pka :3.45±0.36(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChI :1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
InChIKey :SLUINPGXGFUMLL-UHFFFAOYSA-N
SMILES :O=C(NC1=CC=C(C2=CC=CC=C2)C=C1)C(C=CC=C3)=C3C(O)=O
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Kartogenin potently induces differentiation of human mesenchymal stem cells into chondrocytes with an EC50 value of 100 nM. Kartogenin induces chondrogenesis by binding the actin-binding protein, filamin A, which disrupts its interaction with the transcription factor core-binding factor β subunit (CBFβ). When dissociated from filamin A, CBFβ translocates to the nucleus and forms a transcriptional complex with the runt-related transcription factor RUNX1, which enables chondrocyte differentiation. Kartogenin has been shown to promote cartilage repair in a mouse model of osteoarthritis and to protect against cytokine-induced damage in osteoarthritic bovine articular chondrocytes in vitro.Related product price
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![2-[([1,1'-Biphenyl]-4-ylaMino)carbonyl]benzoic Acid](https://img.chemicalbook.com/ProductImageEN/2019-9/small/52a74ed7-749b-4502-bb97-fa685facc639.jpg){kind=small}
