OKADAIC ACID
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- $57 - $1960
- Product name: OKADAIC ACID
- CAS: 78111-17-8
- MF: C44H68O13
- MW: 805
- EINECS:616-589-8
- MDL Number:MFCD00083455
- Synonyms:1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(;Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1;OA;OKADAIC ACID, PROROCENTRUM CONCAVUM;35-Demethyldinophysistoxin 1;35-Demethyl-DTX 1;NSC 677083;9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
27 prices
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Brand
- Adipogen Life Sciences
- Alfa Aesar
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 20μg
- 25μg
- 25ug
- 50μg
- 50ug
- 100μg
- 100ug
- 0.1mg
- 300μg
- 500μg
- 0.5mg
- 500ug
- 1mg
- 25U
- 50microgram
- 50ug(solution)
- 100ug(solution)
- 100microg
- 300microg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0056-C100
- Product descriptionOkadaicacid(freeacid)(highpurity) ≥98%(HPLC)
- Packaging100μg
- Price$185
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60155
- Product descriptionOkadaic acid, 98%
- Packaging50microgram
- Price$121
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60155
- Product descriptionOkadaic acid, 98%
- Packaging100microg
- Price$213
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60155
- Product descriptionOkadaic acid, 98%
- Packaging300microg
- Price$627
- Updated2023-06-20
- Buy
- ManufacturerApexBio Technology
- Product numberA4540
- Product descriptionOkadaic acid
- Packaging50ug(solution)
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4540
- Product descriptionOkadaic acid
- Packaging100ug(solution)
- Price$194
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545972
- Product descriptionOkadaic acid >98%
- Packaging20μg
- Price$127.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545972
- Product descriptionOkadaic acid >98%
- Packaging100μg
- Price$290.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61066
- Product descriptionOkadaic Acid, Free Acid >98% pure
- Packaging50μg
- Price$329.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61066
- Product descriptionOkadaic Acid, Free Acid >98% pure
- Packaging100μg
- Price$368.9
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61066
- Product descriptionOkadaic Acid, Free Acid >98% pure
- Packaging300μg
- Price$595
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb61066
- Product descriptionOkadaic Acid, Free Acid >98% pure
- Packaging1mg
- Price$1395.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10011490
- Product descriptionOkadaic Acid ≥95%
- Packaging25μg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10011490
- Product descriptionOkadaic Acid ≥95%
- Packaging50μg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10011490
- Product descriptionOkadaic Acid ≥95%
- Packaging100μg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number66529
- Product descriptionOkadaic acid
- Packaging0.5mg
- Price$1150
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0056-C100 | Okadaicacid(freeacid)(highpurity) ≥98%(HPLC) | 100μg | $185 | 2021-12-16 | Buy |
| Alfa Aesar | J60155 | Okadaic acid, 98% | 50microgram | $121 | 2023-06-20 | Buy |
| Alfa Aesar | J60155 | Okadaic acid, 98% | 100microg | $213 | 2023-06-20 | Buy |
| Alfa Aesar | J60155 | Okadaic acid, 98% | 300microg | $627 | 2023-06-20 | Buy |
| ApexBio Technology | A4540 | Okadaic acid | 50ug(solution) | $103 | 2021-12-16 | Buy |
| ApexBio Technology | A4540 | Okadaic acid | 100ug(solution) | $194 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545972 | Okadaic acid >98% | 20μg | $127.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545972 | Okadaic acid >98% | 100μg | $290.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb61066 | Okadaic Acid, Free Acid >98% pure | 50μg | $329.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb61066 | Okadaic Acid, Free Acid >98% pure | 100μg | $368.9 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb61066 | Okadaic Acid, Free Acid >98% pure | 300μg | $595 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb61066 | Okadaic Acid, Free Acid >98% pure | 1mg | $1395.7 | 2021-12-16 | Buy |
| Cayman Chemical | 10011490 | Okadaic Acid ≥95% | 25μg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 10011490 | Okadaic Acid ≥95% | 50μg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 10011490 | Okadaic Acid ≥95% | 100μg | $166 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 66529 | Okadaic acid | 0.5mg | $1150 | 2021-12-16 | Buy |
Properties
Melting point :164-166 °C
alpha :D20 +21° (c = 0.33 in CHCl3); D25 +25.4° (c = 0.24 in CHCl3)
Boiling point :672.95°C (rough estimate)
Density :1.0795 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: ≥1 mg/mL
form :translucent film
pka :3.87±0.16(Predicted)
color :translucent
Water Solubility :It is soluble in ethanol (25 mg/ml), DMSO (25 mg/ml), methanol (<1 mg/ml), chloroform, acetone, ethyl acetate, DMF, and dimethylsulfoxide. Insoluble in water, unless first dissolved in organic solvents, such as DMSO or ethanol.
Merck :13,6891
Stability :Stable. Light and heat-sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference :78111-17-8
EPA Substance Registry System :1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, .alpha,5-dihydroxy-.alpha.,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (.alpha.R,2S,5R,6R,8S)- (78111-17-8)
alpha :D20 +21° (c = 0.33 in CHCl3); D25 +25.4° (c = 0.24 in CHCl3)
Boiling point :672.95°C (rough estimate)
Density :1.0795 (rough estimate)
refractive index :1.5940 (estimate)
storage temp. :-20°C
solubility :DMSO: ≥1 mg/mL
form :translucent film
pka :3.87±0.16(Predicted)
color :translucent
Water Solubility :It is soluble in ethanol (25 mg/ml), DMSO (25 mg/ml), methanol (<1 mg/ml), chloroform, acetone, ethyl acetate, DMF, and dimethylsulfoxide. Insoluble in water, unless first dissolved in organic solvents, such as DMSO or ethanol.
Merck :13,6891
Stability :Stable. Light and heat-sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference :78111-17-8
EPA Substance Registry System :1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, .alpha,5-dihydroxy-.alpha.,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (.alpha.R,2S,5R,6R,8S)- (78111-17-8)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junctions, causes vasodilation and is a very potent tumor promoter. Okadaic acid is an extremely useful tool for studying cellular processes that are regulated by phosphorylation. It is shown to activate atypical protein kinase C in adipocytes.More related product prices
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