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ChemicalBook >> CAS DataBase List >> OSI-420

OSI-420

OSI-420 price.
  • $68 - $2728.69
  • Product name: OSI-420
  • CAS: 183321-86-0
  • MF: C21H21N3O4
  • MW: 379.41
  • EINECS:
  • MDL Number:MFCD09841129
  • Synonyms:CP 373420;OSI-420 (free base);Erlotinib O-DesMethyl Metabolite;Erlotinib iMpurity H;Desmethyl Erlotinib (CP-473420, OSI-420);6-O-Desmethyl Erlotinib 1;2-((4-((3-ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethan-1-ol;2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol
Price17 Properties Safety Information Description
17 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • TRC
Package
  • 1MG
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0152394
  • Product description2-(4-(3-ETHYNYLPHENYLAMINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YLOXY)ETHANOL 95.00%
  • Packaging1MG
  • Price$818.61
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0152394
  • Product description2-(4-(3-ETHYNYLPHENYLAMINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YLOXY)ETHANOL 95.00%
  • Packaging10MG
  • Price$2728.69
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1495
  • Product descriptionOSI-420freebase
  • Packaging200mg
  • Price$2006
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO26597
  • Product descriptionDesmethyl erlotinib
  • Packaging5mg
  • Price$294
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO26597
  • Product descriptionDesmethyl erlotinib
  • Packaging10mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO26597
  • Product descriptionDesmethyl erlotinib
  • Packaging25mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO26597
  • Product descriptionDesmethyl erlotinib
  • Packaging50mg
  • Price$1350
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFO26597
  • Product descriptionDesmethyl erlotinib
  • Packaging100mg
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23394
  • Product descriptionDesmethyl Erlotinib ≥98%
  • Packaging1mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23394
  • Product descriptionDesmethyl Erlotinib ≥98%
  • Packaging5mg
  • Price$201
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23394
  • Product descriptionDesmethyl Erlotinib
  • Packaging10mg
  • Price$370
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003183
  • Product descriptionDesmethylErlotinib 98.07%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003183
  • Product descriptionDesmethylErlotinib 98.07%
  • Packaging10mg
  • Price$252
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003183
  • Product descriptionDesmethylErlotinib 98.07%
  • Packaging50mg
  • Price$642
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD37000051
  • Product description2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol 95+%
  • Packaging5mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD37000051
  • Product description2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol 95+%
  • Packaging10mg
  • Price$338
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation CHM0152394 2-(4-(3-ETHYNYLPHENYLAMINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YLOXY)ETHANOL 95.00% 1MG $818.61 2021-12-16 Buy
American Custom Chemicals Corporation CHM0152394 2-(4-(3-ETHYNYLPHENYLAMINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YLOXY)ETHANOL 95.00% 10MG $2728.69 2021-12-16 Buy
ApexBio Technology B1495 OSI-420freebase 200mg $2006 2021-12-16 Buy
Biosynth Carbosynth FO26597 Desmethyl erlotinib 5mg $294 2021-12-16 Buy
Biosynth Carbosynth FO26597 Desmethyl erlotinib 10mg $470 2021-12-16 Buy
Biosynth Carbosynth FO26597 Desmethyl erlotinib 25mg $850 2021-12-16 Buy
Biosynth Carbosynth FO26597 Desmethyl erlotinib 50mg $1350 2021-12-16 Buy
Biosynth Carbosynth FO26597 Desmethyl erlotinib 100mg $1900 2021-12-16 Buy
Cayman Chemical 23394 Desmethyl Erlotinib ≥98% 1mg $68 2024-03-01 Buy
Cayman Chemical 23394 Desmethyl Erlotinib ≥98% 5mg $201 2024-03-01 Buy
Cayman Chemical 23394 Desmethyl Erlotinib 10mg $370 2024-03-01 Buy
ChemScene CS-0003183 DesmethylErlotinib 98.07% 5mg $144 2021-12-16 Buy
ChemScene CS-0003183 DesmethylErlotinib 98.07% 10mg $252 2021-12-16 Buy
ChemScene CS-0003183 DesmethylErlotinib 98.07% 50mg $642 2021-12-16 Buy
Crysdot CD37000051 2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol 95+% 5mg $221 2021-12-16 Buy
Crysdot CD37000051 2-((4-((3-Ethynylphenyl)amino)-7-(2-methoxyethoxy)quinazolin-6-yl)oxy)ethanol 95+% 10mg $338 2021-12-16 Buy
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Properties

Melting point :140-142°C
Density :1.30
storage temp. :-20°C Freezer
solubility :insoluble in H2O; insoluble in EtOH; ≥51 mg/mL in DMSO
form :A crystalline solid

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

OSI-420 is a metabolite of Erlotinib. Erlontinib potently inhibits EGFR autophosphorylation in cultured human head and neck tumor cells, a cell line which exhibits high levels of EGFR. Erlotinib also inhibits the proliferation of PC-9 cell lines, which contain a deletion mutation on exon 19 of the EGFR gene. A combination of Erlotinib and rapamycin produced a synergistic inhibitory effect on cell growth.

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