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ChemicalBook >> CAS DataBase List >> Olmutinib

Olmutinib

$9 - $1100
Product name: Olmutinib
CAS: 1353550-13-6
MF: C26H26N6O2S
MW: 486.59
EINECS:-0
MDL Number:MFCD29918158
Synonyms:HM71224;HM-71224;Olmutinib;Olmutinib, HM71224;N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide dihydrochloride monohydrate;N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide;N-[3-[[2-[[4-(4-Methyl-1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-4-yl]oxy]phenyl]-2-propenamide;HM71224, Olmutinib

Price46 Properties Safety Information Description

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Brand

aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Matrix Scientific
Medical Isotopes, Inc.
TRC

Package

10mM*1mLinDMSO(Solution)
10mM(in1mLDMSO)
25.00mg
10mM*1mLinDMSO(Solid+Solvent)
1mg
5mg
10mg
25mg
50.00mg
50mg
100mg
100.00mg
200mg
250mg
1G

Manufactureraablocks
Product numberAA0021QJ
Product descriptionN-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%
Packaging1mg
Price$9
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0021QJ
Product descriptionN-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%
Packaging5mg
Price$18
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0021QJ
Product descriptionN-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%
Packaging10mg
Price$26
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0021QJ
Product descriptionN-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%
Packaging25mg
Price$48
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0021QJ
Product descriptionN-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%
Packaging50mg
Price$81
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0021QJ
Product descriptionN-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%
Packaging100mg
Price$137
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA0021QJ
Product descriptionN-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%
Packaging250mg
Price$232
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberL18021
Product descriptionOlmutinib 98%
Packaging1G
Price$350
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberL18021
Product descriptionOlmutinib 98%
Packaging25MG
Price$45
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberL18021
Product descriptionOlmutinib 98%
Packaging100MG
Price$115
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number2858DM
Product descriptionOlmutinib
Packaging10mg
Price$370
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB7813
Product descriptionOlmutinib (HM61713, BI 1482694)
Packaging100mg
Price$407
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberB7813
Product descriptionOlmutinib (HM61713, BI 1482694)
Packaging50mg
Price$242
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberB7813
Product descriptionOlmutinib (HM61713, BI 1482694)
Packaging10mM(in1mLDMSO)
Price$72
Updated2026-05-06
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ManufacturerApexBio Technology
Product numberB7813
Product descriptionOlmutinib (HM61713, BI 1482694)
Packaging10mg
Price$110
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberB7813
Product descriptionOlmutinib (HM61713, BI 1482694)
Packaging5mg
Price$66
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA0021QJ	N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%	1mg	$9	2026-05-28	Buy
aablocks	AA0021QJ	N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%	5mg	$18	2026-05-28	Buy
aablocks	AA0021QJ	N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%	10mg	$26	2026-05-28	Buy
aablocks	AA0021QJ	N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%	25mg	$48	2026-05-28	Buy
aablocks	AA0021QJ	N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%	50mg	$81	2026-05-28	Buy
aablocks	AA0021QJ	N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%	100mg	$137	2026-05-28	Buy
aablocks	AA0021QJ	N-(3-(2-(4-(4-methylpiperazin-1-yl)phenylamino)thieno[3,2-d]pyrimidin-4-yloxy)phenyl)acrylamide 98%	250mg	$232	2026-05-28	Buy
ACHEMBLOCK	L18021	Olmutinib 98%	1G	$350	2026-05-27	Buy
ACHEMBLOCK	L18021	Olmutinib 98%	25MG	$45	2026-05-27	Buy
ACHEMBLOCK	L18021	Olmutinib 98%	100MG	$115	2026-05-27	Buy
AK Scientific	2858DM	Olmutinib	10mg	$370	2021-12-16	Buy
ApexBio Technology	B7813	Olmutinib (HM61713, BI 1482694)	100mg	$407	2026-05-06	Buy
ApexBio Technology	B7813	Olmutinib (HM61713, BI 1482694)	50mg	$242	2026-05-06	Buy
ApexBio Technology	B7813	Olmutinib (HM61713, BI 1482694)	10mM(in1mLDMSO)	$72	2026-05-06	Buy
ApexBio Technology	B7813	Olmutinib (HM61713, BI 1482694)	10mg	$110	2026-05-06	Buy
ApexBio Technology	B7813	Olmutinib (HM61713, BI 1482694)	5mg	$66	2026-05-06	Buy

Next Last

Properties

Density :1.336±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥9.11 mg/mL in EtOH with ultrasonic; ≥96.6 mg/mL in DMSO
form :crystalline solid
pka :12.87±0.70(Predicted)
color :Light yellow to yellow
InChIKey :FDMQDKQUTRLUBU-UHFFFAOYSA-N
SMILES :C(NC1=CC=CC(OC2N=C(NC3=CC=C(N4CCN(C)CC4)C=C3)N=C3C=CSC3=2)=C1)(=O)C=C

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

HM71224 is an inhibitor of Bruton's tyrosine kinase (BTK; IC50 = 1.95 nM) that has been shown to prevent B cell activation and osteoclastogenesis. It additionally targets the related kinases BMX, Tec, and TXK (IC50s = 0.64, 4.57, and 4.62 nM, respectively), as well as EGFR (IC50 = 4.96 nM). In a mouse model of rheumatoid arthritis, 3-30 mg/kg HM71224 dose dependently reduced erosive bone changes and prevented bone loss.

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Suppliers and manufacturers

Elucigen bio Shanghai Boyle Chemical Co., Ltd. Chembest Research Laboratories Limited Tetranov Biopharm Dalian Meilun Biotech Co., Ltd. Shanghai Topbiochem Technology Co., Ltd ShangHai Caerulum Pharma Discovery Co., Ltd. Shanghai YuanQi Biotechnology Co., Ltd. Shanghai Lollane Biological Technology Co.,Ltd. Twochem Co.Ltd

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Olmutinib

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