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ChemicalBook >> CAS DataBase List >> Phenformin hydrochloride

Phenformin hydrochloride

Phenformin hydrochloride price.
  • $25.9 - $860
  • Product name: Phenformin hydrochloride
  • CAS: 834-28-6
  • MF: C10H16ClN5
  • MW: 241.72
  • EINECS:212-637-3
  • MDL Number:MFCD00035039
  • Synonyms:1-(diaminomethylene)-2-phenethylguanidine hydrochloride;1-(diaminomethylene)-2-phenethyl-guanidine hydrochloride;1-(diaminomethylidene)-2-phenethylguanidine hydrochloride;1-(diaminomethylidene)-2-phenethyl-guanidine hydrochloride;1-Fenetilbiguanide cloridrato [Italian];1-Phen;meltrol ;n-(2-phenylethyl)-imidodicarbonimidicdiamidmonohydrochloride
21 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 500mg
  • 5g
  • 50g
  • 100g
  • 250g
  • 10mM(in 1mL DMSO)
  • 10mg
  • 50mg
  • 1G
  • 10g
  • 25g
  • ManufacturerAHH
  • Product numberMT-57838
  • Product descriptionPhenformin hydrochloride 98%
  • Packaging250g
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberA624
  • Product descriptionPhenformin hydrochloride
  • Packaging25g
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0025906
  • Product descriptionPHENFORMIN HYDROCHLORIDE 95.00%
  • Packaging1G
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenforminHCl
  • Packaging50mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenforminHCl
  • Packaging10g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenforminHCl
  • Packaging10mM(in 1mL DMSO)
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1373
  • Product descriptionPhenforminHCl
  • Packaging50g
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14997
  • Product descriptionPhenformin (hydrochloride) ≥98%
  • Packaging10g
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14997
  • Product descriptionPhenformin (hydrochloride) ≥98%
  • Packaging50g
  • Price$99
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14997
  • Product descriptionPhenformin (hydrochloride) ≥98%
  • Packaging100g
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1850
  • Product descriptionPhenformin hydrochloride 98.12%
  • Packaging500mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1850
  • Product descriptionPhenformin hydrochloride 98.12%
  • Packaging1g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1850
  • Product descriptionPhenformin hydrochloride 98.12%
  • Packaging5g
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN11690
  • Product descriptionPHenforminHCl
  • Packaging10mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN11690
  • Product descriptionPHenforminHCl
  • Packaging50mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC8990
  • Product descriptionPhenformin hydrochloride >98%
  • Packaging1g
  • Price$300
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-57838 Phenformin hydrochloride 98% 250g $490 2021-12-16 Buy
AK Scientific A624 Phenformin hydrochloride 25g $54 2021-12-16 Buy
American Custom Chemicals Corporation API0025906 PHENFORMIN HYDROCHLORIDE 95.00% 1G $126 2021-12-16 Buy
ApexBio Technology B1373 PhenforminHCl 50mg $40 2021-12-16 Buy
ApexBio Technology B1373 PhenforminHCl 10g $50 2021-12-16 Buy
ApexBio Technology B1373 PhenforminHCl 10mM(in 1mL DMSO) $80 2021-12-16 Buy
ApexBio Technology B1373 PhenforminHCl 50g $150 2021-12-16 Buy
Cayman Chemical 14997 Phenformin (hydrochloride) ≥98% 10g $40 2024-03-01 Buy
Cayman Chemical 14997 Phenformin (hydrochloride) ≥98% 50g $99 2024-03-01 Buy
Cayman Chemical 14997 Phenformin (hydrochloride) ≥98% 100g $139 2024-03-01 Buy
ChemScene CS-1850 Phenformin hydrochloride 98.12% 500mg $50 2021-12-16 Buy
ChemScene CS-1850 Phenformin hydrochloride 98.12% 1g $60 2021-12-16 Buy
ChemScene CS-1850 Phenformin hydrochloride 98.12% 5g $80 2021-12-16 Buy
CSNpharm CSN11690 PHenforminHCl 10mg $35 2021-12-16 Buy
CSNpharm CSN11690 PHenforminHCl 50mg $48 2021-12-16 Buy
DC Chemicals DC8990 Phenformin hydrochloride >98% 1g $300 2021-12-16 Buy

Properties

Melting point :175-178°C
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
color :White to Off-White
Water Solubility :>=10 g/100 mL at 21 ºC
CAS DataBase Reference :834-28-6(CAS DataBase Reference)
EPA Substance Registry System :Phenformin hydrochloride (834-28-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phenformin is an orally administered biguanide derivative with potential to lower blood glucose concentrations in patients with non-insulin-dependent diabetes mellitus. In general, biguanides improve insulin sensitivity and decrease insulin resistance by inhibiting complex 1 of the mitochondrial respiratory chain and inducing AMP-activated protein kinase (AMPK)-dependent signaling. Phenformin, however, has been withdrawn from clinical use because it also inhibits peripheral glucose oxidation and has an associated effect of inducing lactic acidosis when not metabolized sufficiently. Through AMPK activation, phenformin at 300 mg/kg exhibits anticancer activity by inhibiting the growth of MCF-7 and MDAMB231 breast cancer cell xenografts in mice.

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