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ChemicalBook >> CAS DataBase List >> SNS-032

SNS-032

SNS-032 price.
  • $25 - $5966
  • Product name: SNS-032
  • CAS: 345627-80-7
  • MF: C17H24N4O2S2
  • MW: 380.53
  • EINECS:
  • MDL Number:MFCD09833875
  • Synonyms:BMS-3870032 N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide;N-[5-[(5-tert-Butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide SNS-032 (BMS-387032);N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamid;SNS-032, >=99%;N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide;BMS-387032;4-Piperidinecarboxamide, N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-;N-(5-((5-Tert-Butyloxazol-2-yl)methylthio)thiazol-2-yl)piperidine-4-carboxamide
Price43 Properties Safety Information Description
43 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
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  • 10mg
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  • 100mg
  • 200mg
  • 250mg
  • 1g
  • 5g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberX7382
  • Product descriptionN-[5-[(5-Tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide
  • Packaging250mg
  • Price$1077
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA153280
  • Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
  • Packaging1mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA153280
  • Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
  • Packaging5mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA153280
  • Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA153280
  • Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
  • Packaging50mg
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA153280
  • Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
  • Packaging100mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA153280
  • Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
  • Packaging250mg
  • Price$1107
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA153280
  • Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+%
  • Packaging1g
  • Price$1107
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007075
  • Product descriptionBMS-387032 95.00%
  • Packaging1MG
  • Price$148.05
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007075
  • Product descriptionBMS-387032 95.00%
  • Packaging5MG
  • Price$816.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007075
  • Product descriptionBMS-387032 95.00%
  • Packaging1G
  • Price$2880.15
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1980
  • Product descriptionSNS-032(BMS-387032)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1980
  • Product descriptionSNS-032(BMS-387032)
  • Packaging10mM(in 1mL DMSO)
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1980
  • Product descriptionSNS-032(BMS-387032)
  • Packaging25mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1980
  • Product descriptionSNS-032(BMS-387032)
  • Packaging100mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS022470
  • Product descriptionN-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide ≥99%
  • Packaging1mg
  • Price$25
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7382 N-[5-[(5-Tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide 250mg $1077 2021-12-16 Buy
Ambeed A153280 N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% 1mg $25 2021-12-16 Buy
Ambeed A153280 N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% 5mg $25 2021-12-16 Buy
Ambeed A153280 N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% 10mg $59 2021-12-16 Buy
Ambeed A153280 N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% 50mg $159 2021-12-16 Buy
Ambeed A153280 N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% 100mg $440 2021-12-16 Buy
Ambeed A153280 N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% 250mg $1107 2021-12-16 Buy
Ambeed A153280 N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide 99+% 1g $1107 2021-12-16 Buy
American Custom Chemicals Corporation API0007075 BMS-387032 95.00% 1MG $148.05 2021-12-16 Buy
American Custom Chemicals Corporation API0007075 BMS-387032 95.00% 5MG $816.75 2021-12-16 Buy
American Custom Chemicals Corporation API0007075 BMS-387032 95.00% 1G $2880.15 2021-12-16 Buy
ApexBio Technology A1980 SNS-032(BMS-387032) 1unit $28 2021-12-16 Buy
ApexBio Technology A1980 SNS-032(BMS-387032) 10mM(in 1mL DMSO) $95 2021-12-16 Buy
ApexBio Technology A1980 SNS-032(BMS-387032) 25mg $250 2021-12-16 Buy
ApexBio Technology A1980 SNS-032(BMS-387032) 100mg $780 2021-12-16 Buy
Arctom AS022470 N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide ≥99% 1mg $25 2021-12-16 Buy
Next Last

Properties

Melting point :171-173 °C
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :7.33±0.70(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. SNS-032 is an ATP-competitive inhibitor of Cdk9, 2, and 7 with IC50 values of 4, 38, and 62 nM, respectively. It is selective for these kinases and displays no additional activity against a panel of 190 kinases (IC50s = >1,000 nM). SNS-032 can block the cell cycle, inhibit transcription, and induce apoptosis in multiple myeloma RPMI-8226 cells with an IC90 value of 0.3 μM. This compound has been shown to induce apoptosis by inhibiting the transcription of the anti-apoptotic proteins, Mcl-1 and XIAP.

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Suppliers and manufacturers

career henan chemical co
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide
$0.01 /1KG
N-[5-[(5-tert-butyl-1,3-oxazol-2-yl)methylsulfanyl]-1,3-thiazol-2-yl]piperidine-4-carboxamide CAS:345627-80-7
Capot Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Chongqing Chemdad Co., Ltd
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED
ANHUI WITOP BIOTECH CO., LTD
Dideu Industries Group Limited