Slv320
|
- $11 - $2200
- Product name: Slv320
- CAS: 251945-92-3
- MF: C18H20N4O
- MW: 308.38
- EINECS:
- MDL Number:
- Synonyms:Cyclohexanol, 4-((2-phenyl-1H-pyrrolo(2,3-D)pyrimidin-4-yl)amino)-, trans-;Slv320;trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;(1R,4R)-4-(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)cyclohexanol;SC-204288;4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol;SLV320; SLV-320; SLV 320; DERENOFYLLINE;Cyclohexanol, 4-[(2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-, trans-
39 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1mg
- 5mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- 5 mg
- Manufactureraablocks
- Product numberAA002QRH
- Product descriptionDerenofylline 98%
- Packaging1mg
- Price$11
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QRH
- Product descriptionDerenofylline 98%
- Packaging5mg
- Price$13
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QRH
- Product descriptionDerenofylline 98%
- Packaging10mg
- Price$16
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QRH
- Product descriptionDerenofylline ≥98%
- Packaging50mg
- Price$75
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QRH
- Product descriptionDerenofylline ≥98%
- Packaging100mg
- Price$87
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002QRH
- Product descriptionDerenofylline ≥98%
- Packaging250mg
- Price$174
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101922
- Product descriptionDerenofylline 98%
- Packaging1G
- Price$660
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberT101922
- Product descriptionDerenofylline 98%
- Packaging100MG
- Price$110
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4484CR
- Product descriptionDerenofylline
- Packaging50mg
- Price$509
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA887654
- Product descriptionSlv320 98%
- Packaging1g
- Price$635
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA887654
- Product descriptionSlv320 98%
- Packaging250mg
- Price$255
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA887654
- Product descriptionSlv320 98%
- Packaging100mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA887654
- Product descriptionSlv320 98%
- Packaging5mg
- Price$18
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA887654
- Product descriptionSlv320 98%
- Packaging10mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005746
- Product descriptionTRANS-4-[2-[PHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]-CYCLOHEXANOL 95.00%
- Packaging5MG
- Price$505.47
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7373
- Product descriptionSLV 320
- Packaging50mg
- Price$205
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002QRH | Derenofylline 98% | 1mg | $11 | 2026-05-28 | Buy |
| aablocks | AA002QRH | Derenofylline 98% | 5mg | $13 | 2026-05-28 | Buy |
| aablocks | AA002QRH | Derenofylline 98% | 10mg | $16 | 2026-05-28 | Buy |
| aablocks | AA002QRH | Derenofylline ≥98% | 50mg | $75 | 2026-05-28 | Buy |
| aablocks | AA002QRH | Derenofylline ≥98% | 100mg | $87 | 2026-05-28 | Buy |
| aablocks | AA002QRH | Derenofylline ≥98% | 250mg | $174 | 2026-05-28 | Buy |
| ACHEMBLOCK | T101922 | Derenofylline 98% | 1G | $660 | 2026-05-27 | Buy |
| ACHEMBLOCK | T101922 | Derenofylline 98% | 100MG | $110 | 2026-05-27 | Buy |
| AK Scientific | 4484CR | Derenofylline | 50mg | $509 | 2021-12-16 | Buy |
| Ambeed | A887654 | Slv320 98% | 1g | $635 | 2021-12-16 | Buy |
| Ambeed | A887654 | Slv320 98% | 250mg | $255 | 2021-12-16 | Buy |
| Ambeed | A887654 | Slv320 98% | 100mg | $128 | 2021-12-16 | Buy |
| Ambeed | A887654 | Slv320 98% | 5mg | $18 | 2021-12-16 | Buy |
| Ambeed | A887654 | Slv320 98% | 10mg | $27 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005746 | TRANS-4-[2-[PHENYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO]-CYCLOHEXANOL 95.00% | 5MG | $505.47 | 2021-12-16 | Buy |
| ApexBio Technology | B7373 | SLV 320 | 50mg | $205 | 2026-05-06 | Buy |
Properties
Boiling point :532.3±60.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in ethanol
form :Powder
pka :15.15±0.40(Predicted)
color :White to off-white
InChI :1S/C18H20N4O/c23-14-8-6-13(7-9-14)20-18-15-10-11-19-17(15)21-16(22-18)12-4-2-1-3-5-12/h1-5,10-11,13-14,23H,6-9H2,(H2,19,20,21,22)
InChIKey :RBZNJGHIKXAKQE-UHFFFAOYSA-N
SMILES :O[C@H]1CC[C@@H](CC1)NC2=NC(C3=CC=CC=C3)=NC4=C2C=CN4
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :Soluble to 100 mM in DMSO and to 50 mM in ethanol
form :Powder
pka :15.15±0.40(Predicted)
color :White to off-white
InChI :1S/C18H20N4O/c23-14-8-6-13(7-9-14)20-18-15-10-11-19-17(15)21-16(22-18)12-4-2-1-3-5-12/h1-5,10-11,13-14,23H,6-9H2,(H2,19,20,21,22)
InChIKey :RBZNJGHIKXAKQE-UHFFFAOYSA-N
SMILES :O[C@H]1CC[C@@H](CC1)NC2=NC(C3=CC=CC=C3)=NC4=C2C=CN4
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Derenofylline is an adenosine A1 receptor antagonist (Ki = 1 nM). It is selective for adenosine A1 over A2A, A2B, and A3 receptors (Kis = 398, 3,981, and 200 nM, respectively). It decreases adenosine A1 receptor-mediated adenosine-induced bradycardia in rats (ED50 = 0.49 mg/kg) but reduces A2 receptor-mediated adenosine-induced hypotension by only 44.6% when administered at an intravenous dose of 5 mg/kg. It prevents increases in heart levels of collagen I and III in nephrectomized rats when administered at a dose of 10 mg/kg per day. Derenofylline also reduces relative plaque counts in a Zika virus plaque-forming assay in A549 cells (IC50 = 58.6 nM) in an adenosine A1 receptor-independent manner without inducing cytotoxicity when used at concentrations less than 10 μM.More related product prices
Slv320 (R)-(+)-4'-HYDROXYPHENYL-CARVEDILOL CARVEDILOL-D5 Carvedilol b-D-GlucuronideRelated product price
-
Slv320
$11-2200 -
(R)-(+)-4'-HYDROXYPHENYL-CARVEDILOL
$69-1963.5 -
CARVEDILOL-D5
$169-1455
Suppliers and manufacturers
3B Pharmachem (Wuhan) International Co.,Ltd.
EMMX Biotechnology LLC
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Tianjin Kailiqi Biotechnology Co., Ltd.
Shanghai Chaolan Chemical Technology Center
Beijing Minruida Technology Co., Ltd.
Jiangsu aikang biomedical research and development co., LTD
Career Henan Chemica Co
