TAK-063
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- $84 - $2200
- Product name: TAK-063
- CAS: 1238697-26-1
- MF: C23H17FN6O2
- MW: 428.42
- EINECS:
- MDL Number:MFCD28385852
- Synonyms:TAK-063;1-[2-Fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one;Balipodect;TAK 063;TAK063; Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one];CS-1534;TAK-063(Balipodect);TAK063, TAK 063, TAK-063, BALIPODECT
16 prices
Selected condition：
Brand
- AK Scientific
- Axon Medchem
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
Package
- 5mg
- 2x5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 1g
- ManufacturerAK Scientific
- Product number8448DG
- Product descriptionBalipodect
- Packaging25mg
- Price$333
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2399
- Product descriptionTAK063 99%
- Packaging5mg
- Price$137.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2399
- Product descriptionTAK063 99%
- Packaging2x5mg
- Price$220
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22208
- Product descriptionTAK-063 ≥98%
- Packaging50mg
- Price$336
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22208
- Product descriptionTAK-063 ≥98%
- Packaging25mg
- Price$212
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22208
- Product descriptionTAK-063 ≥98%
- Packaging10mg
- Price$135
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22208
- Product descriptionTAK-063 ≥98%
- Packaging5mg
- Price$86
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM164515
- Product description1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one 98%
- Packaging100mg
- Price$1374
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3551
- Product descriptionBalipodect 98.69%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3551
- Product descriptionBalipodect 98.69%
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3551
- Product descriptionBalipodect 98.69%
- Packaging50mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3551
- Product descriptionBalipodect 98.69%
- Packaging100mg
- Price$528
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004136
- Product descriptionTAK-063 98+%
- Packaging50mg
- Price$1050
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004136
- Product descriptionTAK-063 98+%
- Packaging10mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004136
- Product descriptionTAK-063 98+%
- Packaging5mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7945
- Product descriptionTAK-063 >98%
- Packaging1g
- Price$2200
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8448DG | Balipodect | 25mg | $333 | 2021-12-16 | Buy |
| Axon Medchem | Axon2399 | TAK063 99% | 5mg | $137.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon2399 | TAK063 99% | 2x5mg | $220 | 2021-12-16 | Buy |
| Cayman Chemical | 22208 | TAK-063 ≥98% | 50mg | $336 | 2024-03-01 | Buy |
| Cayman Chemical | 22208 | TAK-063 ≥98% | 25mg | $212 | 2024-03-01 | Buy |
| Cayman Chemical | 22208 | TAK-063 ≥98% | 10mg | $135 | 2024-03-01 | Buy |
| Cayman Chemical | 22208 | TAK-063 ≥98% | 5mg | $86 | 2024-03-01 | Buy |
| Chemenu | CM164515 | 1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one 98% | 100mg | $1374 | 2021-12-16 | Buy |
| ChemScene | CS-3551 | Balipodect 98.69% | 5mg | $84 | 2021-12-16 | Buy |
| ChemScene | CS-3551 | Balipodect 98.69% | 10mg | $108 | 2021-12-16 | Buy |
| ChemScene | CS-3551 | Balipodect 98.69% | 50mg | $300 | 2021-12-16 | Buy |
| ChemScene | CS-3551 | Balipodect 98.69% | 100mg | $528 | 2021-12-16 | Buy |
| Crysdot | CD31004136 | TAK-063 98+% | 50mg | $1050 | 2021-12-16 | Buy |
| Crysdot | CD31004136 | TAK-063 98+% | 10mg | $350 | 2021-12-16 | Buy |
| Crysdot | CD31004136 | TAK-063 98+% | 5mg | $245 | 2021-12-16 | Buy |
| DC Chemicals | DC7945 | TAK-063 >98% | 1g | $2200 | 2021-12-16 | Buy |
Properties
Boiling point :612.3±65.0 °C(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:55.0(Max Conc. mg/mL);128.38(Max Conc. mM)
form :A crystalline solid
pka :-0.34±0.12(Predicted)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:55.0(Max Conc. mg/mL);128.38(Max Conc. mM)
form :A crystalline solid
pka :-0.34±0.12(Predicted)
Safety Information
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Description
TAK-063 is a potent inhibitor of phosphodiesterase 10A (PDE10A; IC50 = 0.3 nM). It is >15,000-fold selective for PDE10A over other PDEs and exhibits <50% inhibition at 91 receptors, ion channels, and enzymes at a concentration of 10 μM. TAK-063 (0.3 mg/kg) increases cAMP and cGMP levels by 1.3- and 2.14-fold, respectively, in the striatum of mice. It reverses hyperlocomotion induced by PCP (Item Nos. 14276 | ISO60194) with a minimum effective dose (MED) of 0.3 mg/kg, p.o., in wild-type mice but has no effect in PDE10A knockout mice at doses up to 1 mg/kg. TAK-063 also reverses hyperlocomotion induced by (+)-MK-801 (MED = 0.1 mg/kg, p.o.) but has no effect on plasma prolactin or glucose levels in rats.Related product price
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Suppliers and manufacturers
career henan chemical co
![Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one]](https://img.chemicalbook.com/ProductImageEN/2019-12/small/c21f3c3c-c06c-43b8-88b3-cbd7f8184d59.png)
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Shenzhen Shengda Pharma Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
ShenZhen Trendseen Biological Technology Co.,Ltd.
LEAPCHEM CO., LTD.
Aladdin Scientific
$1.00 /1KG
Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one] CAS:1238697-26-1
Pyridone 6[1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-(1-phenyl-1H-pyrazol-5-yl)pyridazin-4(1H)-one] CAS:1238697-26-1