TAK-220
|
- $135 - $1802
- Product name: TAK-220
- CAS: 333994-00-6
- MF: C31H41ClN4O3
- MW: 553.14
- EINECS:
- MDL Number:MFCD28502079
- Synonyms:TAK-220;1-ACETYL-N-(3-(4-(4-CARBAMOYLBENZYL)PIPERIDIN-1-YL)PROPYL)-N-(3-CHLORO-4-METHYLPHENYL)PIPERIDINE-4-CARBOXAMIDE;TAK 220;TAK220;4-Piperidinecarboxamide, 1-acetyl-N-[3-[4-[[4-(aminocarbonyl)phenyl]methyl]-1-piperidinyl]propyl]-N-(3-chloro-4-methylphenyl)-
29 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
Package
- 10mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 50mg
- 1mL(10mMinDMSO)
- 25mg
- 100mg
- Manufactureraablocks
- Product numberAA00C6IV
- Product descriptionTAK-220 ≥98%
- Packaging1mg
- Price$169
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number1559AL
- Product description1-Acetyl-N-(3-(4-(4-carbamoylbenzyl)piperidin-1-yl)propyl)-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide
- Packaging1mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberBA1921
- Product descriptionTAK-220
- Packaging5mg
- Price$315
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA1921
- Product descriptionTAK-220
- Packaging1mL(10mMinDMSO)
- Price$346
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA1921
- Product descriptionTAK-220
- Packaging1mg
- Price$135
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberBA1921
- Product descriptionTAK-220
- Packaging10mg
- Price$450
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-19974
- Product descriptionTAK-220 99.94%
- Packaging25mg
- Price$646
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19974
- Product descriptionTAK-220 99.94%
- Packaging50mg
- Price$969
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19974
- Product descriptionTAK-220 99.94%
- Packaging100mg
- Price$1359
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19974
- Product descriptionTAK-220 99.94%
- Packaging5mg
- Price$228
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19974
- Product descriptionTAK-220 99.94%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$264
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19974
- Product descriptionTAK-220 99.94%
- Packaging10mg
- Price$342
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-19974
- Product descriptionTAK-220 99.94%
- Packaging10mM*1mLinDMSO(Solution)
- Price$278
- Updated2026-05-26
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611449
- Product descriptionTAK-220
- Packaging50mg
- Price$1802
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611449
- Product descriptionTAK-220
- Packaging5mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28448
- Product descriptionTAK-220 ≥98%
- Packaging1mg
- Price$169
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C6IV | TAK-220 ≥98% | 1mg | $169 | 2026-05-28 | Buy |
| AK Scientific | 1559AL | 1-Acetyl-N-(3-(4-(4-carbamoylbenzyl)piperidin-1-yl)propyl)-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide | 1mg | $268 | 2021-12-16 | Buy |
| ApexBio Technology | BA1921 | TAK-220 | 5mg | $315 | 2026-05-06 | Buy |
| ApexBio Technology | BA1921 | TAK-220 | 1mL(10mMinDMSO) | $346 | 2026-05-06 | Buy |
| ApexBio Technology | BA1921 | TAK-220 | 1mg | $135 | 2026-05-06 | Buy |
| ApexBio Technology | BA1921 | TAK-220 | 10mg | $450 | 2026-05-06 | Buy |
| Arctom | HY-19974 | TAK-220 99.94% | 25mg | $646 | 2026-05-26 | Buy |
| Arctom | HY-19974 | TAK-220 99.94% | 50mg | $969 | 2026-05-26 | Buy |
| Arctom | HY-19974 | TAK-220 99.94% | 100mg | $1359 | 2026-05-26 | Buy |
| Arctom | HY-19974 | TAK-220 99.94% | 5mg | $228 | 2026-05-26 | Buy |
| Arctom | HY-19974 | TAK-220 99.94% | 10mM*1mLinDMSO(Solid+Solvent) | $264 | 2026-05-26 | Buy |
| Arctom | HY-19974 | TAK-220 99.94% | 10mg | $342 | 2026-05-26 | Buy |
| Arctom | HY-19974 | TAK-220 99.94% | 10mM*1mLinDMSO(Solution) | $278 | 2026-05-26 | Buy |
| Biorbyt Ltd | orb611449 | TAK-220 | 50mg | $1802 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb611449 | TAK-220 | 5mg | $569.5 | 2021-12-16 | Buy |
| Cayman Chemical | 28448 | TAK-220 ≥98% | 1mg | $169 | 2026-04-30 | Buy |
Properties
Melting point :166-167 °C(Solv: ethyl acetate (141-78-6); ethanol (64-17-5))
Boiling point :757.8±60.0 °C(Predicted)
Density :1.208±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :16.16±0.50(Predicted)
color :White to off-white
Boiling point :757.8±60.0 °C(Predicted)
Density :1.208±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble
form :A crystalline solid
pka :16.16±0.50(Predicted)
color :White to off-white
Safety Information
| Symbol(GHS): | ||||||||
|---|---|---|---|---|---|---|---|---|
| Signal word: | ||||||||
| Hazard statements: |
|
|||||||
| Precautionary statements: |
|
Description
TAK-220 is an orally bioavailable antagonist of chemokine (C-C motif) receptor 5 (CCR5). It binds to CCR5 (IC50 = 3.5 nM for the human receptor in CHO cells), but not CCR1, CCR2b, CCR3, CCR4, or CCR7. TAK-220 inhibits the binding of chemokine (C-C motif) ligand 5 (CCL5) and CCL3 to CCR5 (IC50s = 3.5 and 1.4 nM, respectively) but does not inhibit binding of CCL4. It inhibits HIV-1 envelope-mediated membrane fusion in a macrophage (M-tropic) R5, but not in a T cell (T-tropic) X4, strain of HIV-1 (IC50s = 0.42 and >1,000 nM, respectively). TAK-220 inhibits the replication of six strains of R5 HIV-1 clinical isolates (EC90 overall mean = 13 nM) and the R5 JR-FL laboratory-adapted strain (EC50 = 0.6 nM), but not of X4 HIV-1 clinical isolates or the X4 IIIB laboratory-adapted strain (EC50s = >10,000 nM for both), in human peripheral blood mononuclear cells (PBMCs).More related product prices
TAK-220Related product price
-
TAK-220
$135-1802