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ChemicalBook >> CAS DataBase List >> Trimethoprim

Trimethoprim

Trimethoprim price.
  • $6 - $1330
  • Product name: Trimethoprim
  • CAS: 738-70-5
  • MF: C14H18N4O3
  • MW: 290.32
  • EINECS:212-006-2
  • MDL Number:MFCD00036761
  • Synonyms:TRIMETHOPRIMRESEARCH GRADE;TRIMETHOPRIMMICRONIZED;5-[(3,4,5-TriMethoxyphenyl)Methyl]-;TriMethopriM COS;TriMethopriM 0;TMP (triMethopriM);Trimethoprim solution,1000ppm;Trimethoprim Solution, 100ppm
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Brand
  • AK Scientific
  • Alfa Aesar
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  • 25gm:
  • ManufacturerAK Scientific
  • Product numberJ10046
  • Product descriptionTrimethoprim
  • Packaging25mg
  • Price$19.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63053
  • Product descriptionTrimethoprim
  • Packaging1g
  • Price$35
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63053
  • Product descriptionTrimethoprim
  • Packaging5g
  • Price$92
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67175
  • Product descriptionTrimethoprim, 50 mg/ml in DMSO sterile-filtered
  • Packaging1ml
  • Price$149
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63053
  • Product descriptionTrimethoprim
  • Packaging25g
  • Price$352
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67175
  • Product descriptionTrimethoprim, 50 mg/ml in DMSO sterile-filtered
  • Packaging5x1ml
  • Price$504
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA327622
  • Product descriptionTrimethoprim 98+%
  • Packaging5g
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA327622
  • Product descriptionTrimethoprim 98+%
  • Packaging10g
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA327622
  • Product descriptionTrimethoprim 98+%
  • Packaging25g
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA327622
  • Product descriptionTrimethoprim 98+%
  • Packaging100g
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA327622
  • Product descriptionTrimethoprim 98+%
  • Packaging500g
  • Price$150
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIT0154
  • Product descriptionTrimethoprim 99.8%
  • Packaging5g
  • Price$56
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIT0154
  • Product descriptionTrimethoprim 99.8%
  • Packaging10g
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIT0154
  • Product descriptionTrimethoprim 99.8%
  • Packaging25g
  • Price$203
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS021142
  • Product descriptionTrimethoprim ≥98%
  • Packaging1g
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS021142
  • Product descriptionTrimethoprim ≥98%
  • Packaging5g
  • Price$9
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J10046 Trimethoprim 25mg $19.8 2021-12-16 Buy
Alfa Aesar J63053 Trimethoprim 1g $35 2023-06-20 Buy
Alfa Aesar J63053 Trimethoprim 5g $92 2023-06-20 Buy
Alfa Aesar J67175 Trimethoprim, 50 mg/ml in DMSO sterile-filtered 1ml $149 2024-03-01 Buy
Alfa Aesar J63053 Trimethoprim 25g $352 2023-06-20 Buy
Alfa Aesar J67175 Trimethoprim, 50 mg/ml in DMSO sterile-filtered 5x1ml $504 2024-03-01 Buy
Ambeed A327622 Trimethoprim 98+% 5g $9 2021-12-16 Buy
Ambeed A327622 Trimethoprim 98+% 10g $12 2021-12-16 Buy
Ambeed A327622 Trimethoprim 98+% 25g $16 2021-12-16 Buy
Ambeed A327622 Trimethoprim 98+% 100g $46 2021-12-16 Buy
Ambeed A327622 Trimethoprim 98+% 500g $150 2021-12-16 Buy
Apolloscientific BIT0154 Trimethoprim 99.8% 5g $56 2021-12-16 Buy
Apolloscientific BIT0154 Trimethoprim 99.8% 10g $95 2021-12-16 Buy
Apolloscientific BIT0154 Trimethoprim 99.8% 25g $203 2021-12-16 Buy
Arctom AS021142 Trimethoprim ≥98% 1g $6 2021-12-16 Buy
Arctom AS021142 Trimethoprim ≥98% 5g $9 2021-12-16 Buy

Properties

Melting point :199-203 °C
Boiling point :432.41°C (rough estimate)
Density :1.1648 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :white powder
pka :6.6(at 25℃)
color :colorless or white
Water Solubility :<0.1 g/100 mL at 24 ºC
Merck :14,9709
BRN :625127
BCS Class :2
Stability :Stable. Incompatible with strong oxidizing agents, acids.
CAS DataBase Reference :738-70-5(CAS DataBase Reference)
NIST Chemistry Reference :Trimethoprim(738-70-5)
EPA Substance Registry System :Trimethoprim (738-70-5)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

Trimethoprim is a synthetic antibiotic that inhibits dihydrofolate reductase (DHFR), which is necessary for the synthesis of purines, amino acids, and thymidylic acid. Trimethoprim shows prominent selectivity for bacterial DHFR over mammalian DHFR (IC50s = 5 and 30,000 nM, respectively). Trimethoprim, commonly used in combination with sulfamethoxazole to minimize acquired resistance, has long been used against urinary tract infections. It may also have prophylactic applications, for example in patients receiving biologic agents during inflammation.

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