UNC3230
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- $52 - $1360
- Product name: UNC3230
- CAS: 1031602-63-7
- MF: C17H20N4O2S
- MW: 344.43
- EINECS:
- MDL Number:MFCD15031190
- Synonyms:UNC3230;2-anilino-5-(cyclohexanecarbonylamino)-1,3-thiazole-4-carboxamide;5-[(Cyclohexylcarbonyl)amino]-2-(phenylamino)-thiazolecarboxamide;4-Thiazolecarboxamide, 5-[(cyclohexylcarbonyl)amino]-2-(phenylamino)-;5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide;hyperalgesia,thermal,UNC3230,DRG,antinociceptive,neuron,inhibit,UNC-3230,PIP2,anticancer,glycolysis,PIP4K2C,PIP5K1C,Inhibitor;UNC3230, 10 mM in DMSO
38 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- ApexBio Technology
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 1mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 1G
- 1 unit
- 10 mg
- 50 mg
- Manufactureraablocks
- Product numberAA0096BA
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide ≥98%
- Packaging5mg
- Price$61
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0096BA
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98%
- Packaging25mg
- Price$95
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0096BA
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98%
- Packaging50mg
- Price$161
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0096BA
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98%
- Packaging100mg
- Price$272
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0096BA
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide
- Packaging1mg
- Price$52
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY232633
- Product descriptionUNC 3230 98%
- Packaging100MG
- Price$475
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY232633
- Product descriptionUNC 3230 98%
- Packaging250MG
- Price$650
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY232633
- Product descriptionUNC 3230 98%
- Packaging1G
- Price$1360
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number4840DG
- Product description2-Anilino-5-(cyclohexanecarbonylamino)-1,3-thiazole-4-carboxamide
- Packaging100mg
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1195872
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98%
- Packaging25mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1195872
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98%
- Packaging100mg
- Price$513
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1195872
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98%
- Packaging250mg
- Price$885
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1195872
- Product description5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98%
- Packaging50mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4941
- Product descriptionUNC 3230
- Packaging10mg
- Price$214
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4941
- Product descriptionUNC 3230
- Packaging50mg
- Price$903
- Updated2026-05-06
- Buy
- ManufacturerBiosynth
- Product numberFC166267
- Product descriptionUNC 3230
- Packaging250mg
- Price$1047.5
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0096BA | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide ≥98% | 5mg | $61 | 2026-05-28 | Buy |
| aablocks | AA0096BA | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98% | 25mg | $95 | 2026-05-28 | Buy |
| aablocks | AA0096BA | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98% | 50mg | $161 | 2026-05-28 | Buy |
| aablocks | AA0096BA | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98% | 100mg | $272 | 2026-05-28 | Buy |
| aablocks | AA0096BA | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide | 1mg | $52 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y232633 | UNC 3230 98% | 100MG | $475 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y232633 | UNC 3230 98% | 250MG | $650 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y232633 | UNC 3230 98% | 1G | $1360 | 2026-05-27 | Buy |
| AK Scientific | 4840DG | 2-Anilino-5-(cyclohexanecarbonylamino)-1,3-thiazole-4-carboxamide | 100mg | $455 | 2021-12-16 | Buy |
| Ambeed | A1195872 | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98% | 25mg | $226 | 2021-12-16 | Buy |
| Ambeed | A1195872 | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98% | 100mg | $513 | 2021-12-16 | Buy |
| Ambeed | A1195872 | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98% | 250mg | $885 | 2021-12-16 | Buy |
| Ambeed | A1195872 | 5-(Cyclohexanecarboxamido)-2-(phenylamino)thiazole-4-carboxamide 98% | 50mg | $340 | 2021-12-16 | Buy |
| ApexBio Technology | B4941 | UNC 3230 | 10mg | $214 | 2026-05-06 | Buy |
| ApexBio Technology | B4941 | UNC 3230 | 50mg | $903 | 2026-05-06 | Buy |
| Biosynth | FC166267 | UNC 3230 | 250mg | $1047.5 | 2026-06-04 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO:30.0(Max Conc. mg/mL);87.1(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);87.1(Max Conc. mM)
Ethanol:0.2(Max Conc. mg/mL);0.58(Max Conc. mM) form :A crystalline solid
color :Off-white to light yellow
InChIKey :RZCNASHHHSKTGP-UHFFFAOYSA-N
SMILES :O=C(N)C1=C(NC(C2CCCCC2)=O)SC(NC3=CC=CC=C3)=N1
solubility :DMSO:30.0(Max Conc. mg/mL);87.1(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);87.1(Max Conc. mM)
Ethanol:0.2(Max Conc. mg/mL);0.58(Max Conc. mM) form :A crystalline solid
color :Off-white to light yellow
InChIKey :RZCNASHHHSKTGP-UHFFFAOYSA-N
SMILES :O=C(N)C1=C(NC(C2CCCCC2)=O)SC(NC3=CC=CC=C3)=N1
Safety Information
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Description
Phosphatidylinositol-4-phosphate 5-kinase type-1 γ (PIP5K1C) is a lipid kinase that generates phosphatidylinositol-4,5-bisphosphate (PIP2) in nociceptive dorsal root ganglia (DRG). Pain sensitization is regulated by multiple signaling pathways that are initiated by phospholipase C-mediated hydrolysis of PIP2. UNC3230 is a small molecule inhibitor of PIP5K1C (IC50 = 41 nM, Kd = 51 nM). It does not inhibit any other lipid kinases that regulate phosphoinositide levels, including phosphatidylinositol 3-kinases. At 100 nM, UNC3230 decreases PIP2 membrane levels in cultured DRG neurons by 45% and significantly reduces calcium signaling. At 2 nM, it displays antinociceptive effects in mouse models of chronic pain when administered intrathecally or injected into inflamed hindpaw.Suppliers and manufacturers
BOC Sciences
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Topbiochem Technology Co., Ltd
Shanghai Lollane Biological Technology Co.,Ltd.
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
Tianjin Kailiqi Biotechnology Co., Ltd.
Shanghai SuperLan Chemcial Technique Centre
