URB447
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- $91 - $1530
- Product name: URB447
- CAS: 1132922-57-6
- MF: C25H21ClN2O
- MW: 400.9
- EINECS:
- MDL Number:
- Synonyms:URB447;[4-amino-1-[(4-chlorophenyl)methyl]-2-methyl-5-phenylpyrrol-3-yl]-phenylmethanone;Methanone, [4-amino-1-[(4-chlorophenyl)methyl]-2-methyl-5-phenyl-1H-pyrrol-3-yl]phenyl-
20 prices
Selected condition：
Brand
- aablocks
- AK Scientific
- Arctom
- Cayman Chemical
- ChemScene
- TRC
- Usbiological
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- Manufactureraablocks
- Product numberAA0079DC
- Product descriptionURB447 ≥98%
- Packaging5mg
- Price$91
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0079DC
- Product descriptionURB447 ≥98%
- Packaging50mg
- Price$707
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0079DC
- Product descriptionURB447 ≥98%
- Packaging25mg
- Price$399
- Updated2026-05-28
- Buy
- ManufacturerAK Scientific
- Product number3105DC
- Product description{4-Amino-1-[(4-chlorophenyl)methyl]-2-methyl-5-phenyl-1H-pyrrol-3-yl}(phenyl)methanone
- Packaging25mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-122964
- Product descriptionURB447 99.5%
- Packaging25mg
- Price$727
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-122964
- Product descriptionURB447 99.5%
- Packaging50mg
- Price$1342
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-122964
- Product descriptionURB447 99.5%
- Packaging5mg
- Price$179
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-122964
- Product descriptionURB447 99.5%
- Packaging10mg
- Price$331
- Updated2026-05-26
- Buy
- ManufacturerCayman Chemical
- Product number13261
- Product descriptionURB447 ≥98%
- Packaging5mg
- Price$91
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number13261
- Product descriptionURB447 ≥98%
- Packaging10mg
- Price$169
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number13261
- Product descriptionURB447 ≥98%
- Packaging25mg
- Price$399
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number13261
- Product descriptionURB447 ≥98%
- Packaging50mg
- Price$707
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0090761
- Product descriptionURB447 99.5%
- Packaging25mg
- Price$829
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0090761
- Product descriptionURB447 99.5%
- Packaging50mg
- Price$1530
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0090761
- Product descriptionURB447 99.5%
- Packaging10mg
- Price$377
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0090761
- Product descriptionURB447 99.5%
- Packaging5mg
- Price$204
- Updated2026-06-04
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0079DC | URB447 ≥98% | 5mg | $91 | 2026-05-28 | Buy |
| aablocks | AA0079DC | URB447 ≥98% | 50mg | $707 | 2026-05-28 | Buy |
| aablocks | AA0079DC | URB447 ≥98% | 25mg | $399 | 2026-05-28 | Buy |
| AK Scientific | 3105DC | {4-Amino-1-[(4-chlorophenyl)methyl]-2-methyl-5-phenyl-1H-pyrrol-3-yl}(phenyl)methanone | 25mg | $500 | 2021-12-16 | Buy |
| Arctom | HY-122964 | URB447 99.5% | 25mg | $727 | 2026-05-26 | Buy |
| Arctom | HY-122964 | URB447 99.5% | 50mg | $1342 | 2026-05-26 | Buy |
| Arctom | HY-122964 | URB447 99.5% | 5mg | $179 | 2026-05-26 | Buy |
| Arctom | HY-122964 | URB447 99.5% | 10mg | $331 | 2026-05-26 | Buy |
| Cayman Chemical | 13261 | URB447 ≥98% | 5mg | $91 | 2026-04-30 | Buy |
| Cayman Chemical | 13261 | URB447 ≥98% | 10mg | $169 | 2026-04-30 | Buy |
| Cayman Chemical | 13261 | URB447 ≥98% | 25mg | $399 | 2026-04-30 | Buy |
| Cayman Chemical | 13261 | URB447 ≥98% | 50mg | $707 | 2026-04-30 | Buy |
| ChemScene | CS-0090761 | URB447 99.5% | 25mg | $829 | 2026-06-04 | Buy |
| ChemScene | CS-0090761 | URB447 99.5% | 50mg | $1530 | 2026-06-04 | Buy |
| ChemScene | CS-0090761 | URB447 99.5% | 10mg | $377 | 2026-06-04 | Buy |
| ChemScene | CS-0090761 | URB447 99.5% | 5mg | $204 | 2026-06-04 | Buy |
Properties
Melting point :128-130 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
Boiling point :568.6±50.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :1.11±0.18(Predicted)
Boiling point :568.6±50.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml
form :A crystalline solid
pka :1.11±0.18(Predicted)
Safety Information
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Description
URB447 is a mixed central cannabinoid (CB1) receptor antagonist/peripheral cannabinoid (CB2) receptor agonist with IC50 values of 313 and 41 nM, respectively. At 20 mg/kg delivered intraperitoneally to ob/ob mice and Swiss mice, URB447 reduces food intake and body-weight gain with an efficacy comparable to rimonabant, which is an inverse agonist for the CB1. Marketed as an anti-obesity drug and appetite suppressant, rimonabant was subsequently suspended from distribution due to serious psychiatric side effects attributed to its indiscriminate activity on CB1 receptors in the central nervous system (CNS). Unlike rimonabant, URB447 does not penetrate the blood-brain barrier (to antagonize CB1 receptors in the CNS); instead, it appears to selectively block peripheral CB1 receptors such as those located in the gastrointestinal tract.More related product prices
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