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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
1036390-38-1

1(2H)-Isoquinolinone, 7-amino-4-bromo- synthesis

6synthesis methods
1036390-36-9 Synthesis
4-BROMO-7-NITROISOQUINOLIN-1(2H)-ONE

1036390-36-9
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1(2H)-Isoquinolinone, 7-amino-4-bromo-

1036390-38-1
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Yield:1036390-38-1 88%

Reaction Conditions:

with tin(II) chloride dihdyrate;ammonium chloride in methanol at 20 - 50;

References:

Wurtz, Nicholas R.;Parkhurst, Brandon L.;Jiang, Wen;DeLucca, Indawati;Zhang, Xiaojun;Ladziata, Vladimir;Cheney, Daniel L.;Bozarth, Jeffrey R.;Rendina, Alan R.;Wei, Anzhi;Luettgen, Joseph M.;Wu, Yiming;Wong, Pancras C.;Seiffert, Dietmar A.;Wexler, Ruth R.;Priestley, E. Scott [ACS Medicinal Chemistry Letters,2016,vol. 7,# 12,p. 1077 - 1081] Location in patent:supporting information

2-Methyl-5-nitrobenzoic acid

1975-52-6
284 suppliers
$12.00/1g

1(2H)-Isoquinolinone, 7-amino-4-bromo-

1036390-38-1
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References
77324-87-9 Synthesis
Methyl 5-nitro-2-methylbenzoate

77324-87-9
208 suppliers
$6.00/1g

1(2H)-Isoquinolinone, 7-amino-4-bromo-

1036390-38-1
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References
64688-68-2 Synthesis
Benzoyl chloride, 2-methyl-5-nitro- (9CI)

64688-68-2
23 suppliers
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1(2H)-Isoquinolinone, 7-amino-4-bromo-

1036390-38-1
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References
1036388-63-2

1036388-63-2
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1(2H)-Isoquinolinone, 7-amino-4-bromo-

1036390-38-1
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References