1,4-bis(pyridin-4-ylmethyl)piperazine synthesis
2synthesis methods
- Product Name:1,4-bis(pyridin-4-ylmethyl)piperazine
- CAS Number:357429-12-0
- Molecular formula:C16H20N4
- Molecular Weight:268.36
Yield:357429-12-0 54%
Reaction Conditions:
Stage #1: piperazine;4-picolylchloride hydrochloridewith sodium hydroxide in water at 20; pH=8 - 9;
Stage #2: in water;Reflux;
References:
Tripathy, Debakanta;Ramkumar, Venkatachalam;Chand, Dillip K. [Crystal Growth and Design,2013,vol. 13,# 8,p. 3763 - 3772]
