1-(4-BROMOBUTOXY)-2-CHLOROBENZENE synthesis
1synthesis methods
- Product Name:1-(4-BROMOBUTOXY)-2-CHLOROBENZENE
- CAS Number:23468-00-0
- Molecular formula:C10H12BrClO
- Molecular Weight:263.56
Yield:23468-00-0 80%
Reaction Conditions:
Stage #1: 2-monochlorophenolwith sodium hydride in mineral oil at 20; for 0.5 h;Schlenk technique;Inert atmosphere;
Stage #2: 1,4-dibromo-butane in mineral oil; for 2 h;Schlenk technique;Inert atmosphere;
References:
Yi, Jun;Lu, Xi;Sun, Yan-Yan;Xiao, Bin;Liu, Lei [Angewandte Chemie - International Edition,2013,vol. 52,# 47,p. 12409 - 12413][Angew. Chem.,2013,vol. 125,# 47,p. 12635 - 12639,5] Location in patent:supporting information