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1-[4-(Trifluoromethyl)phenyl]ethane-1,2-diol synthesis

8synthesis methods
2-[4-(trifluoromethyl)phenyl]oxirane

111991-14-1
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1-[4-(Trifluoromethyl)phenyl]ethane-1,2-diol

175605-64-8
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Yield:175605-64-8 100%

Reaction Conditions:

with sulfuric acid in tetrahydrofuran;water;

References:

Deregnaucourt, Justine;Archelas, Alain;Barbirato, Fabien;Paris, Jean-Marc;Furstoss, Roland [Advanced Synthesis and Catalysis,2006,vol. 348,# 10-11,p. 1165 - 1169]