1-ETHYL-1H-PYRAZOLE-3-CARBALDEHYDE synthesis
- Product Name:1-ETHYL-1H-PYRAZOLE-3-CARBALDEHYDE
- CAS Number:942319-16-6
- Molecular formula:C6H8N2O
- Molecular Weight:124.14
942319-16-6
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1007489-05-5
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Yield:1007489-05-5 98 mg
Reaction Conditions:
with sodium tetrahydroborate in methanol at 25; for 2.5 h;
Steps:
40.1 (1 -Ethyl- lH-pyrazol-3-yl)methanol
Sodium borohydride (126 mg) was added to a solution of l -ethylpyrazole-3- carbaldehyde (275 mg) in methanol (5 mL), and stirred at 25°C for 2.5 hrs. This reaction solution was extracted with ethyl acetate (20 mL, three times) and an aqueous ammonium chloride solution (20 mL), and the organic layers were pooled, dried over anhydrous magnesium sulfate, and subjected to vacuum filtration and vacuum distillation. The residue was purified using column chromatography to obtain the desired compound (98 mg).
References:
WO2014/3483,2014,A1 Location in patent:Page/Page column 41
942319-16-6
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1172973-66-8
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942319-16-6
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1313410-15-9
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942319-16-6
74 suppliers
$60.00/1g
1527518-34-8
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