1H-Indazole-6-carboxylic acid, 5-broMo-, Methyl ester synthesis
- Product Name:1H-Indazole-6-carboxylic acid, 5-broMo-, Methyl ester
- CAS Number:1000342-30-2
- Molecular formula:C9H7BrN2O2
- Molecular Weight:255.07
18595-18-1
372 suppliers
$8.00/10g
1000342-30-2
89 suppliers
$12.00/250mg
Yield:-
Steps:
Multi-step reaction with 2 steps
1.1: N-Bromosuccinimide / N,N-dimethyl-formamide / 20 °C / Cooling with ice
2.1: boron trifluoride diethyl etherate; tert.-butylnitrite / dichloromethane / -78 - 20 °C / Inert atmosphere
2.2: 20 °C
References:
Rooney, Lisa;Vidal, Agnès;D'Souza, Anne-Marie;Devereux, Nick;Masick, Brian;Boissel, Valerie;West, Ryan;Head, Victoria;Stringer, Rowan;Lao, Jianmin;Petrus, Matt J.;Patapoutian, Ardem;Nash, Mark;Stoakley, Natalie;Panesar, Moh;Verkuyl, J. Martin;Schumacher, Andrew M.;Petrassi, H. Michael;Tully, David C. [Journal of Medicinal Chemistry,2014,vol. 57,# 12,p. 5129 - 5140]
474330-54-6
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$62.77/0.5g
1000342-30-2
89 suppliers
$12.00/250mg