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ChemicalBook CAS DataBase List 2-Bromo-5,6-dihydro-8H-[1,2,4]triazolo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester
1575613-02-3

2-Bromo-5,6-dihydro-8H-[1,2,4]triazolo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester synthesis

4synthesis methods
24424-99-5 Synthesis
Di-tert-butyl dicarbonate

24424-99-5
859 suppliers
$13.50/25G

2-Bromo-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyrazine

1260663-45-3
18 suppliers
inquiry

2-Bromo-5,6-dihydro-8H-[1,2,4]triazolo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester

1575613-02-3
18 suppliers
inquiry

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Yield:1575613-02-3 85.6%

Reaction Conditions:

with triethylamine in dichloromethane at 20; for 2 h;

References:

Cao, Xufeng;Sun, Zhaoshuan;Cao, Yongbing;Wang, Ruilian;Cai, Tongkai;Chu, Wenjing;Hu, Wenhao;Yang, Yushe [Journal of Medicinal Chemistry,2014,vol. 57,# 9,p. 3687 - 3706] Location in patent:supporting information

1359702-68-3 Synthesis
2-bromo-[1,2,4]triazolo[1,5-a]pyrazine

1359702-68-3
38 suppliers
$180.00/100mg

2-Bromo-5,6-dihydro-8H-[1,2,4]triazolo[1,5-a]pyrazine-7-carboxylic acid tert-butyl ester

1575613-02-3
18 suppliers
inquiry