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ChemicalBook CAS DataBase List [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine

[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine synthesis

1synthesis methods
Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
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[2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine

170729-79-0
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Yield: 850 mg

Reaction Conditions:

with sodium tetrahydroborate in methanol at 0 - 5;

References:

Gangula, Srinivas;Elati, Chandrashekhar R.;Mudunuru, Satish Varma;Nardela, Anitha;Dongamanti, Ashok;Bhattacharya, Apurba;Bandichhor, Rakeshwar [Synthetic Communications,2010,vol. 40,# 15,p. 2254 - 2268] Location in patent:experimental part

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