
(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine synthesis
- Product Name:(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
- CAS Number:327623-37-0
- Molecular formula:C20H18F7NO2
- Molecular Weight:437.35
![2H-1,4-Oxazine, 2-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-](/CAS/20210305/GIF/934540-47-3.gif)
934540-47-3
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327623-37-0
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![2-(R)-[1-(R)-(3,5-Bis(trifluoromethyl)phenyl)ethoxy]-3-(S)-fluorophenylmorpholine](/CAS/GIF/171338-27-5.gif)
171338-27-5
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$80.00/1mg
Yield:-
Reaction Conditions:
with hydrogen;5% palladium over charcoal in methanol at 30; for 3 h;
Steps:
24
EXAMPLE 24: PREPARATION OF THE COMPOUND OF FORMULA IIIa 16 g of the compound of Formula IVa obtained from Example 23 , 16 g of 5% palladium on carbon, and 160 ml of methanol were charged into a clean and dry hydrogenation vessel. Dry hydrogen gas of pressure 3.0 kg/cm2 was passed into the reaction suspension for a period of 3 hours at about 30 0C. After the EPO
References:
WO2007/44829,2007,A2 Location in patent:Page/Page column 43
![Benzoic acid, 3,5-bis(trifluoromethyl)-, (2S,3R)-3-(4-fluorophenyl)-4-[(1R)-1-phenylethyl]-2-morpholinyl ester](/CAS/20210305/GIF/1523569-82-5.gif)
1523569-82-5
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327623-37-0
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403-42-9
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$5.00/10g

327623-37-0
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447-43-8
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$12.00/1g

327623-37-0
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