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ChemicalBook CAS DataBase List (1H-BENZOIMIDAZOL-2-YLMETHYL)-PHENYL-AMINE
5805-59-4

(1H-BENZOIMIDAZOL-2-YLMETHYL)-PHENYL-AMINE synthesis

4synthesis methods
-

Yield:5805-59-4 85%

Reaction Conditions:

Stage #1: 2-chloromethyl-1H-benzimidazole;anilinewith potassium iodide in ethanol; for 6 h;Reflux;
Stage #2: with potassium hydroxide in ethanol;water; for 2 h;

References:

Achar, Kavitha C.S.;Hosamani, Kallappa M.;Seetharamareddy, Harisha R. [European Journal of Medicinal Chemistry,2010,vol. 45,# 5,p. 2048 - 2054] Location in patent:experimental part