2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE synthesis
- Product Name:2-(2-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE
- CAS Number:26060-06-0
- Molecular formula:C12H7NO2S
- Molecular Weight:229.25
5271-67-0
257 suppliers
$5.00/1g
118-92-3
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$23.00/250g
26060-06-0
25 suppliers
$28.60/5MG
Yield:26060-06-0 99%
Reaction Conditions:
with acetic anhydride;triethylamine in ethyl acetate;
Steps:
1 2-(2'-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE
Example 1 2-(2'-THIENYL)-4H-3,1-BENZOXAZIN-4-ONE A solution of anthranilic acid (2.0 g, 15 mmol), 2-thienylcarbonyl chloride (2.2 g, 15 mmol), and triethylamine (1.5 g, 15 mmol) in ethyl acetate (9 mL) was stirred for 1 h. The solution was filtered and concentrated to a solid (3.7 g, 99%). The solid (1 g, 4 mmol) was heated at reflux with acetic anhydride (20 mL) for 18 h. The reaction mixture was concentrated, washed with water, and dried to give the title compound (0.92 g, 99%); m.p. 129-130° C.
References:
US5939421,1999,A
3437-95-4
251 suppliers
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201230-82-2
1 suppliers
inquiry
615-43-0
428 suppliers
$5.00/5g
26060-06-0
25 suppliers
$28.60/5MG
4298-52-6
163 suppliers
$24.00/1g
143321-89-5
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inquiry
26060-06-0
25 suppliers
$28.60/5MG
41242-35-7
1 suppliers
inquiry
26060-06-0
25 suppliers
$28.60/5MG
5271-67-0
257 suppliers
$5.00/1g
201230-82-2
1 suppliers
inquiry
615-43-0
428 suppliers
$5.00/5g
26060-06-0
25 suppliers
$28.60/5MG