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ChemicalBook CAS DataBase List 2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID

2-(4-NITRO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID synthesis

8synthesis methods
-

Yield:70097-13-1 85%

Reaction Conditions:

Stage #1: indole-2,3-dionewith hexadecyltrimethylammonium hydroxide in lithium hydroxide monohydrate at 20; for 0.166667 h;Sonication;Green chemistry;Pfitzinger Quinoline Synthesis;
Stage #2: 1-(4-nitrophenyl)ethan-1-one in lithium hydroxide monohydrate at 35; for 2 h;Sonication;Green chemistry;Pfitzinger Quinoline Synthesis;Temperature;

References:

More, Priyanka A.;Shankarling, Ganapati S. [New Journal of Chemistry,2017,vol. 41,# 21,p. 12380 - 12383] Location in patent:supporting information

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