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Pyruvic acid

Uses
Pyruvic acid
Pyruvic acid structure
CAS No.
127-17-3
Chemical Name:
Pyruvic acid
Synonyms
pyruvic;NSC 179;CH3COCOOH;FEMA 2970;PYRUVIC ACID;Pyruvia Acid;ACID PYRUVATE;PyruvicAcid>PYRUVIC ACID BRI;PYRORACEMIC ACID
CBNumber:
CB5257557
Molecular Formula:
C3H4O3
Formula Weight:
88.06
MOL File:
127-17-3.mol

Pyruvic acid Properties

Melting point:
11-12 °C (lit.)
Boiling point:
165 °C (lit.)
Density 
1.267 g/mL at 25 °C (lit.)
FEMA 
2970 | PYRUVIC ACID
refractive index 
n20/D 1.428(lit.)
Flash point:
183 °F
storage temp. 
2-8°C
solubility 
Miscible with chloroform and methanol.
pka
2.39(at 25℃)
form 
Liquid
color 
Clear colorless to light yellow or amber
PH
1.2 (90g/l, H2O, 20℃)
Merck 
14,8021
JECFA Number
936
BRN 
506211
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases. Refrigerate.
InChIKey
LCTONWCANYUPML-UHFFFAOYSA-N
CAS DataBase Reference
127-17-3(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)
PYRUVIC ACID
FDA 21 CFR
172.515
EWG's Food Scores
1
FDA UNII
8558G7RUTR
NIST Chemistry Reference
Pyruvic acid(127-17-3)
EPA Substance Registry System
Propanoic acid, 2-oxo- (127-17-3)
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H227-H318-H314
Precautionary statements  P309-P280-P305+P351+P338-P310
Hazard Codes  C
Risk Statements  34
Safety Statements  26-36/37/39-45-25-27
RIDADR  UN 3265 8/PG 2
WGK Germany  3
RTECS  UZ0829800
Autoignition Temperature 305 °C
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29335995

Pyruvic acid price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 107360 Pyruvic acid 98% 127-17-3 25g $46.4 2021-03-22 Buy
Sigma-Aldrich 8.20170 Pyruvic acid for synthesis 127-17-3 100 mL $62.44 2021-03-22 Buy
Sigma-Aldrich 107360 Pyruvic acid 98% 127-17-3 100g $73.3 2021-03-22 Buy
Sigma-Aldrich W297070 Pyruvic acid natural, ≥95%, FG 127-17-3 25 g $85 2021-03-22 Buy
Sigma-Aldrich W297003 Pyruvic acid ≥97%, FG 127-17-3 250 g $88.9 2021-03-22 Buy

Pyruvic acid Chemical Properties,Uses,Production

Uses

Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. The liver can convert Pyruvic acid to alanine by amination. A diagnostic agent for Parkinson disease.

Chemical Properties

Colorless to light yellow liquid

Chemical Properties

Pyruvic acid has a sour, acetic odor (similar to acetic acid). It has a pleasant, sour taste with a burning, somewhat sweet note. It tends to darken and decompose unless kept free of minor contaminants and in tightly sealed containers

Occurrence

Isolated from cane sugar fermentation broth and from a few plants; also reported found in peppermint, raw asparagus, leaves and stalk of celery, onion, rutabaga, milk, cream, buttermilk, wheaten bread, blue cheeses, cheddar cheese, cottage cheese, provolone cheese, yogurt, beef, Virginia tobacco, beer, white wine, botrytised wine, cocoa and sake.

Uses

pyruvic acid is an alpha hydroxy acid that can be irritating and is considered difficult to work with. It has a larger molecular size than the most commonly used AHAs. Sodium pyruvate is more commonly used, and is an organic salt.

Uses

Biochemical research.

Definition

A fundamen- tal intermediate in protein and carbohydrate metabolism in the cell.

Preparation

By distillation of tartaric acid in the presence of potassium acid sulfate as a dehydrating agent; from acetyl chloride and potassium cyanide to yield the nitrile, which is subsequently acid hydrolyzed to the acid; pyruvic acid must be rectified under vacuum.

Aroma threshold values

Aroma characteristics at 1.0%: acidic, sweet, caramellic and sour.

Taste threshold values

Taste characteristics at 5 ppm: sharp acidic, sour fruity, with sour creamy and caramellic nuances.

Biotechnological Applications

Pyruvic acid is a key position in cell metabolism and is involved in many catabolic and anabolic pathways, including glycolysis, gluconeogenesis, amino acid, and protein metabolism. Pyruvic acid is employed for the production of L-tryptophan, L-tyrosine, and 3,4-dihydroxyphenyl alanine in various industries. The diet supplementation with pyruvic acid increased fat loss and minimized the associated loss of body protein. Pyruvic acid is also used in biochemical researches and medicine as a substrate for assaying activities of such enzymes as pyruvate dehydrogenase, pyruvate carboxylase, and pyruvate decarboxylase (Nakazawa et al. 1972; Yamada et al. 1972; Stanko et al. 1992).
Y. lipolytica oxidize glucose and form pyruvic acid (75–80 %) and a-ketoglutaric acid (20–25 %) under thiamine deficiency conditions. The synthesis of the acid was triggered by a decrease in intracellular thiamine concentration to 3.0 lg per 1 g biomass. An approximately 3-fold increase in the amount of the biomass was associated with a subsequent decrease in thiamine content to the level of 1.0 lg per 1 g biomass, whose maximum production of pyruvic acid was 50 g/L in this condition. In addition to glucose, thiamine-auxotrophic yeasts are capable of synthesizing pyruvic acid when grown on glycerol and propionic acid. Technicalgrade glycerol is the most promising raw material for pyruvic acid production. Pyruvic acid was obtained at a concentration of 61 g/L with a yield of 71 % from glycerol (Morgunov et al. 2004; Finogenova et al. 2005).

Purification Methods

Distil it twice, then fractionally crystallise it by partial freezing. [Beilstein 3 IV 1505.]

Pyruvic acid Preparation Products And Raw materials

Raw materials

Preparation Products


Pyruvic acid Suppliers

Global( 437)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai Worldyang Chemical Co.,Ltd.
+86-13651600618
CHINA 832 58
Capot Chemical Co.,Ltd.
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View Lastest Price from Pyruvic acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-21 Pyruvic acid
127-17-3
US $10.00-15.00 / KG 0.5KG >99% 20tons Anhui Rencheng Technology Co., Ltd
2021-09-14 Pyruvic acid
127-17-3
US $650.00 / kg/bag 25公斤/袋 99% 55200T Baoji Guokang Healthchem co.,ltd
2021-09-07 pyruvic acid
127-17-3
US $30.00 / Kg/Bag 1Kg/Bag >99% 20000kg Per Month Hebei Zhanyao Biotechnology Co. Ltd

Pyruvic acid Spectrum


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