2,5-Dimethyl-2,5-hexanediol synthesis
- Product Name:2,5-Dimethyl-2,5-hexanediol
- CAS Number:110-03-2
- Molecular formula:C8H18O2
- Molecular Weight:146.23
142-30-3
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110-03-2
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$6.00/25g
Yield:110-03-2 84%
Reaction Conditions:
with palladium on activated charcoal;hydrogen in ethyl acetate at 20; under 7500.75 Torr; for 12 h;Autoclave;
Steps:
2
37.4 g (263 mmol) of A3 was added to an autoclave, and 60 mL of ethyl acetate was added. 0.285 g (2.63 mmol, 1 mol %) of Pd/C catalyst was further added, and hydrogen gas was slowly added so that it becomes 10 bar. When the reaction was performed at room temperature and hydrogen gas was consumed, it was allowed to continuously maintain 10 bar. When the hydrogenation reaction was performed for 12 hours and then the reaction was completed, hydrogen gas was removed, and the autoclave was opened. The resulting mixture was filtered using a celite pad. The filtered ethyl acetate solution was concentrated to obtain 32.3 g (yield: 84%) of A4 of Reaction Scheme 5. 1H NMR (500 MHz, CDCl3) 2.89 (2H, bs), 1.71 (4H, s), 1.25 (12H, s)
References:
US2021/24451,2021,A1 Location in patent:Paragraph 0064; 0067-0068
75-65-0
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110-03-2
335 suppliers
$6.00/25g
6975-92-4
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$45.00/50mg
110-03-2
335 suppliers
$6.00/25g
3404-78-2
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$90.00/500mg
110-03-2
335 suppliers
$6.00/25g