ChemicalBook CAS DataBase List 2,6-DICHLORO-4-(TRIFLUOROMETHYL)NICOTINAMIDE

2,6-DICHLORO-4-(TRIFLUOROMETHYL)NICOTINAMIDE synthesis

2synthesis methods

Product Name:2,6-DICHLORO-4-(TRIFLUOROMETHYL)NICOTINAMIDE
CAS Number:158063-67-3
Molecular formula:C7H3Cl2F3N2O
Molecular Weight:259.01

2,6-Dichloro-4-(trifluoromethyl)nicotinonitrile

13600-42-5
164 suppliers
$9.00/250mg

2,6-DICHLORO-4-(TRIFLUOROMETHYL)NICOTINAMIDE

158063-67-3
76 suppliers
$35.00/250mg

Yield: 90.09%

Reaction Conditions:

with sulfuric acid at 100; for 1 h;

Steps:

1.3 (3) Preparation of 2,6-dichloro-4-(trifluoromethyl)nicotinamide
500 mL round bottom flask, 79.6 g (330 mmo 1) of 2,6-dichloro-3-cyano-4-(trifluoromethyl)pyridine concentrated sulfuric acid 400 grams heated to 100 degrees with stirring l h, after the reaction was added to the water to precipitate a solid, filtered and washed, dried to give a white solid 77 grams, yield 90.09%.

References:

Hebei Lan Tai Chemical Technology Co., Ltd.;Guo Ming;Meng Shuiqiang;Tian Penghui;Hou Jianjun CN107382848, 2017, A Location in patent:Paragraph 0043; 0048-0049

3335-46-4 Synthesis

3-CYANO-2,6-DIHYDROXY-4-(TRIFLUOROMETHYL)PYRIDINE

3335-46-4
104 suppliers
$9.00/1g

158063-67-3
76 suppliers
$35.00/250mg

References

2,6-DICHLORO-4-(TRIFLUOROMETHYL)NICOTINAMIDE Related Search:

2,6-Dichloro-4-(trifluoromethyl)pyridine 2 6-DICHLOROPYRIDINE-3-CARBOXALDEHYDE 2,6-Dichloronicotinamide 4-(TRIFLUOROMETHYL)NICOTINAMIDE 2-Chloro-4-(trifluoromethyl)pyridine