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1531-62-0

2-Butyl-3-methylquinoline synthesis

3synthesis methods
-

Yield:1531-62-0 55%

Reaction Conditions:

Stage #1: 2-Aminobenzyl alcohol;heptan-3-onewith potassium hydroxide;copper dichloride in 1,4-dioxane at 20;
Stage #2: with oxygen in 1,4-dioxane;Reflux;

References:

Wang, Tianli;Zhuo, Lian-Gang;Li, Zhiwei;Chen, Fei;Ding, Ziyuan;He, Yanmei;Fan, Qing-Hua;Xiang, Junfeng;Yu, Zhi-Xiang;Chan, Albert S. C. [Journal of the American Chemical Society,2011,vol. 133,# 25,p. 9878 - 9891] Location in patent:supporting information; experimental part